Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 7/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL87329 | 0.95 | RAD52 (0.41) | ZDHHC20ZDHHC2KDM4ERAD52TGM2 | |
| SCHEMBL9321561 | 0.87 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2KDM4ETGM2CYP1A2 | |
| SCHEMBL83920 | 0.81 | RAD52 (0.44) | KDM4ERAD52CYP1A2ALDH1A1MAPT | |
| SCHEMBL511330 | 0.79 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2KDM4ETGM2ALDH1A1 | |
| SCHEMBL512105 | 0.79 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2KDM4ETGM2ALDH1A1 | |
| SCHEMBL5057346 | 0.79 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2KDM4ETGM2ALDH1A1 | |
| SCHEMBL510455 | 0.79 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2KDM4ETGM2ALDH1A1 | |
| SCHEMBL8850072 | 0.79 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2KDM4ETGM2ALDH1A1 | |
| SCHEMBL8850445 | 0.79 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2KDM4ETGM2ALDH1A1 | |
| SCHEMBL11676767 | 0.79 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2KDM4ETGM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430963-B1 | HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS | ISP INVESTMENTS INC (US) | 1994-01-12 | — | — | EP | disclosed |
| US-4923694-A | HAIR CONDITIONERS; (3-METHACRYLAMIDOPROPYL) TRIMETHYL AMMONIUM CHLORIDE-VINYLPYRROLIDONE COPOLYMER | GAF CHEMICALS CORPORATION (US) | 1990-05-08 | — | — | US | disclosed |