SCHEMBL9320710

SCHEMBL9320710

OCc1ccc2c(c1)C=C2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
RECQL P46063 1/20 0.37
TYR P14679 1/20 0.37
ENPP2 Q13822 1/20 0.37
ACHE P22303 1/20 0.36
CA12 O43570 2/20 0.35
CA2 P00918 2/20 0.35
CA4 P22748 2/20 0.35
CA6 P23280 2/20 0.35
CA5A P35218 2/20 0.35
CA7 P43166 2/20 0.35
CA9 Q16790 2/20 0.35
CA14 Q9ULX7 2/20 0.35
CA5B Q9Y2D0 2/20 0.35
CA3 P07451 1/20 0.35
TTR P02766 1/20 0.35
PRSS1 P07477 2/20 0.34
PRSS2 P07478 2/20 0.34
PRSS3 P35030 2/20 0.34
CHKA P35790 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22863712 0.78 CA12 (0.40) TSHRRECQLTYRENPP2ACHE
SCHEMBL9719495 0.78 GFER (0.35) RECQLHSD17B10LTA4H
SCHEMBL9719458 0.78 CA2 (0.42) TSHRCA2CA4CA6CA1
SCHEMBL9719478 0.76 CA2 (0.40) TSHRCA2CA4CA6CA1
SCHEMBL7801458 0.74
SCHEMBL9090377 0.74 CA1 (0.33) TSHRCA2TTRCA1
Hydrochloric Acid SCHEMBL9091024 0.72
SCHEMBL9811869 0.72 HPGD (0.55) TSHRCA2HSD17B10
SCHEMBL1972537 0.70 KMT2A (0.30)
SCHEMBL9719503 0.70 IDH1 (0.39) CA2CA4CA6CA9PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117986848-A Pultruded polyurethane door and window composite material and preparation method thereof 河北聚久复合材料有限公司 2024-05-07 CN claimed
US-5349095-A Process for preparing hydroxyalkylbenzocyclobutenes THE DOW CHEMICAL COMPANY (US) 1994-09-20 US claimed
US-5264613-A Process for preparing ester of hydroxymethylbenzocyclobutenes THE DOW CHEMICAL COMPANY (US) 1993-11-23 US claimed
CN-117986848-A Pultruded polyurethane door and window composite material and preparation method thereof 河北聚久复合材料有限公司 2024-05-07 CN disclosed
CN-117986848-A Pultruded polyurethane door and window composite material and preparation method thereof 河北聚久复合材料有限公司 2024-05-07 CN disclosed
WO-2015030469-A1 COMPOUND FOR ORGANIC ELECTRICAL ELEMENT, ORGANIC ELECTRICAL ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 (KR) 2015-03-05 WO disclosed
US-5349095-A Process for preparing hydroxyalkylbenzocyclobutenes THE DOW CHEMICAL COMPANY (US) 1994-09-20 US disclosed
US-5264613-A Process for preparing ester of hydroxymethylbenzocyclobutenes THE DOW CHEMICAL COMPANY (US) 1993-11-23 US disclosed
US-5264613-A Process for preparing ester of hydroxymethylbenzocyclobutenes THE DOW CHEMICAL COMPANY (US) 1993-11-23 US disclosed
EP-0251357-B1 ENGINEERING THERMOPLASTICS CONTAINING PENDANT BENZOCYCLOBUTENE GROUPS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-07-17 EP disclosed
EP-0251357-A1 Engineering thermoplastics containing pendant benzocyclobutene groups SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-01-07 EP disclosed
US-4708994-A CURING, CROSSLINKING; SOLVENT RESISTANCE SHELL OIL COMPANY (US) 1987-11-24 US disclosed