Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1847856 | 0.87 | ALDH1A1 (0.44) | ALDH1A1RECQLLTA4HMTNR1AMTNR1B | |
| SCHEMBL11515377 | 0.87 | TAAR1 (0.44) | TAAR1HTR2ALTA4H | |
| Methyl Alcohol SCHEMBL11163562 | 0.80 | ALDH1A1 (0.40) | TAAR1ALDH1A1MTNR1AMTNR1BLMNA | |
| SCHEMBL28716659 | 0.79 | ALDH1A1 (0.43) | ALDH1A1RECQLLTA4HMTNR1AMTNR1B | |
| SCHEMBL20449085 | 0.79 | TAAR1 (0.39) | TAAR1HTR2ALTA4HMTNR1AMTNR1B | |
| SCHEMBL28036219 | 0.79 | TAAR1 (0.39) | TAAR1HTR2ALTA4HMTNR1AMTNR1B | |
| SCHEMBL166063 | 0.79 | CDK5 (0.41) | ALDH1A1RECQLMTNR1AMTNR1BLMNA | |
| SCHEMBL5286697 | 0.79 | TAAR1 (0.39) | TAAR1HTR2ALTA4HMTNR1AMTNR1B | |
| SCHEMBL28716660 | 0.79 | ALDH1A1 (0.43) | ALDH1A1RECQLLTA4HMTNR1AMTNR1B | |
| Methyl Alcohol SCHEMBL11227349 | 0.79 | ALDH1A1 (0.39) | TAAR1ALDH1A1MTNR1AMTNR1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427480-B1 | 2-Hydroxy-3-phenoxypropylamino compounds | ICI PLC (GB) | 1994-01-12 | — | — | EP | disclosed |
| EP-0427480-A1 | 2-Hydroxy-3-phenoxypropylamino compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-15 | — | — | EP | disclosed |