Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 17/20 | 0.76 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.59 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.59 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.59 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.59 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.59 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.59 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321863 | 1.00 | TACR1 (0.76) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| SCHEMBL9322696 | 0.89 | TACR1 (0.67) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| SCHEMBL9322680 | 0.89 | TACR1 (0.67) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| SCHEMBL9743578 | 0.87 | TACR1 (0.76) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| SCHEMBL9323260 | 0.86 | TACR1 (0.66) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| SCHEMBL9322688 | 0.85 | TACR1 (0.70) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| SCHEMBL9743147 | 0.85 | TACR1 (0.64) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| SCHEMBL9322903 | 0.82 | TACR1 (0.60) | TACR1CYP2D6 | |
| SCHEMBL9322906 | 0.82 | TACR1 (0.60) | TACR1CYP2D6 | |
| SCHEMBL9322896 | 0.82 | TACR1 (0.60) | TACR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409931-B1 | QUINUCLIDINE THERAPEUTIC AGENTS | PFIZER (US) | 1994-02-16 | — | — | EP | claimed |