Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 9/20 | 0.60 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322906 | 1.00 | TACR1 (0.60) | TACR1CHRNB2CHRNA7CHRNA4ATM | |
| SCHEMBL9322903 | 1.00 | TACR1 (0.60) | TACR1CHRNB2CHRNA7CHRNA4ATM | |
| SCHEMBL5203589 | 0.85 | TACR1 (0.69) | TACR1CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL9322963 | 0.84 | TACR1 (0.53) | TACR1CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL9322808 | 0.83 | TACR1 (0.60) | TACR1 | |
| SCHEMBL9323198 | 0.83 | TACR1 (0.60) | TACR1 | |
| SCHEMBL9321863 | 0.82 | TACR1 (0.76) | TACR1CYP2D6 | |
| SCHEMBL9321850 | 0.82 | TACR1 (0.76) | TACR1CYP2D6 | |
| Hydrochloric Acid SCHEMBL9323145 | 0.82 | TACR1 (0.56) | TACR1NPC1MTORRAB9ATP53 | |
| SCHEMBL9321890 | 0.82 | TACR1 (0.56) | TACR1NPC1MTORRAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409931-B1 | QUINUCLIDINE THERAPEUTIC AGENTS | PFIZER (US) | 1994-02-16 | — | — | EP | claimed |
| EP-0409931-B1 | QUINUCLIDINE THERAPEUTIC AGENTS | PFIZER (US) | 1994-02-16 | — | — | EP | disclosed |
| US-5162339-A | Substance P Antagonists, Gastrointestinal and Central Nervous System Disorders, Antiinflammatory Agents, Analgesics | PFIZER INC. (US) | 1992-11-10 | — | — | US | disclosed |