Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | RAD1 | O60671 | 1/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23853327 | 0.87 | ENPP2 (0.56) | ALDH1A1KMT2AGAAHTTSMN1; SMN2 | |
| SCHEMBL8615558 | 0.86 | ENPP2 (0.43) | ALDH1A1KMT2AGAARAD51ENPP2 | |
| SCHEMBL14437899 | 0.78 | ENPP2 (0.74) | ALDH1A1KMT2AHTTSMN1; SMN2ENPP2 | |
| SCHEMBL9321648 | 0.78 | ENPP2 (0.74) | ALDH1A1KMT2AHTTSMN1; SMN2ENPP2 | |
| SCHEMBL26977995 | 0.77 | ENPP2 (0.72) | ALDH1A1KMT2AHTTSMN1; SMN2ENPP2 | |
| SCHEMBL17255098 | 0.77 | ENPP2 (0.72) | ALDH1A1KMT2AHTTSMN1; SMN2ENPP2 | |
| SCHEMBL15282738 | 0.77 | ENPP2 (0.72) | ALDH1A1KMT2AHTTSMN1; SMN2ENPP2 | |
| SCHEMBL8613096 | 0.77 | RAD1 (0.47) | ALDH1A1KMT2ARAD51ENPP2MEN1 | |
| SCHEMBL9321937 | 0.76 | ENPP2 (0.41) | ALDH1A1KMT2ASMN1; SMN2RAD51ENPP2 | |
| SCHEMBL10966689 | 0.75 | KDM4E (0.63) | ALDH1A1KMT2AGAAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5359131-A | Sulfonic acid derivatives in the treatment of viral diseases | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-10-25 | — | — | US | disclosed |