Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 12/20 | 0.63 |
| ▸ | PDK2 | Q15119 | 12/20 | 0.63 |
| ▸ | PDK3 | Q15120 | 12/20 | 0.63 |
| ▸ | PDK4 | Q16654 | 12/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10827862 | 0.84 | PDK1 (0.70) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL28316139 | 0.80 | PDK1 (0.60) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL618106 | 0.78 | PDK1 (0.70) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL7880575 | 0.76 | PDK1 (0.68) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL3323425 | 0.75 | CA1 (0.58) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL5423774 | 0.74 | PDK1 (0.57) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL3717777 | 0.73 | PDK1 (0.55) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL6347849 | 0.73 | PDK1 (0.65) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL9360380 | 0.73 | HTT (0.55) | LMNAHTTPOLBMEN1ALDH1A1 | |
| SCHEMBL14677858 | 0.71 | POLB (0.58) | PDK1PDK2PDK3PDK4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302742-A | Process for the preparation of N-acylated p-amino-phenols | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-12 | — | — | US | disclosed |