Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.69 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | NQO2 | P16083 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321897 | 1.00 | ESR1 (0.69) | ESR1ESR2PTGS1CYP19A1PTGS2 | |
| SCHEMBL9262344 | 0.90 | ESR1 (0.57) | ESR1ESR2PTGS1CYP19A1PTGS2 | |
| SCHEMBL9262340 | 0.90 | ESR1 (0.57) | ESR1ESR2PTGS1CYP19A1PTGS2 | |
| SCHEMBL19659874 | 0.82 | ESR1 (0.49) | ESR1ESR2PTGS1CYP19A1PTGS2 | |
| SCHEMBL9113341 | 0.82 | ESR1 (1.00) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL574346 | 0.82 | ESR1 (1.00) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL19660027 | 0.80 | CYP2D6 (0.54) | ESR1ESR2PTGS1PTGS2LMNA | |
| SCHEMBL22773276 | 0.80 | CYP2D6 (0.54) | ESR1ESR2PTGS1PTGS2LMNA | |
| SCHEMBL28201867 | 0.78 | CYP19A1 (0.48) | ESR1ESR2PTGS1CYP19A1LMNA | |
| SCHEMBL9245167 | 0.77 | ESR1 (0.42) | ESR1ESR2CYP19A1NQO2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579743-A1 | DIAMINO-ALPHA-ALKYLSTILBENES | THE DOW CHEMICAL COMPANY (US) | 1994-01-26 | — | — | EP | disclosed |