SCHEMBL9322148

SCHEMBL9322148

CCCCCCCCCCCCOc1ccc(S(=O)(=O)Nc2ccc(CC[CH]CCS(=O)(=O)CCCCCC)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.52
LMNA P02545 2/20 0.52
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
FFAR1 O14842 1/20 0.47
FFAR4 Q5NUL3 1/20 0.47
ADRB2 P07550 5/20 0.46
ADRB1 P08588 5/20 0.46
ADRB3 P13945 5/20 0.46
CYP3A4 P08684 2/20 0.46
TSHR P16473 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
HTT P42858 1/20 0.46
HDAC1 Q13547 1/20 0.45
MAPT P10636 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7652595 0.84 LMNA (0.64) SMN1; SMN2LMNANPC1RAB9AFFAR1
SCHEMBL8411814 0.81 LMNA (0.60) SMN1; SMN2LMNANPC1RAB9AFFAR1
SCHEMBL9322092 0.80 SMN1; SMN2 (0.59) SMN1; SMN2LMNANPC1RAB9AFFAR1
SCHEMBL9730729 0.79 LMNA (0.60) SMN1; SMN2LMNANPC1RAB9AFFAR1
SCHEMBL8749393 0.76 LMNA (0.62) SMN1; SMN2LMNANPC1RAB9ACYP3A4
SCHEMBL8389469 0.76 LMNA (0.69) SMN1; SMN2LMNANPC1RAB9AADRB2
SCHEMBL4810166 0.76 LMNA (0.69) SMN1; SMN2LMNANPC1RAB9AADRB2
SCHEMBL7177748 0.76 LMNA (0.69) SMN1; SMN2LMNANPC1RAB9AADRB2
SCHEMBL9845769 0.75 LMNA (0.64) SMN1; SMN2LMNANPC1RAB9ACYP3A4
SCHEMBL7175640 0.74 LMNA (0.70) SMN1; SMN2LMNANPC1RAB9AADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0321190-B1 Silver halide color photographic light-sensitive material KONISHIROKU PHOTO IND (JP) 1994-02-09 EP disclosed