Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322277 | 0.90 | SIGMAR1 (0.44) | HRH3KDM4E | |
| SCHEMBL761884 | 0.84 | KDM4E (0.47) | HRH3KDM4EMAOBHRH2HRH1 | |
| SCHEMBL25844752 | 0.82 | HRH3 (0.49) | HRH3KDM4EMAOBHTR7 | |
| SCHEMBL9322345 | 0.80 | HRH3 (0.45) | HRH3HRH1 | |
| SCHEMBL12449634 | 0.80 | KDM4E (0.50) | HRH3KDM4EHTR7 | |
| SCHEMBL13077 | 0.80 | KDM4E (0.50) | HRH3KDM4EHTR7 | |
| SCHEMBL13995508 | 0.80 | KDM4E (0.50) | HRH3KDM4EHTR7 | |
| SCHEMBL10771016 | 0.79 | HRH3 (0.39) | HRH3 | |
| SCHEMBL9374424 | 0.78 | HRH3 (0.53) | HRH3KDM4EMAOBHRH2HRH1 | |
| SCHEMBL9324674 | 0.78 | HRH3 (0.38) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |