Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.36 |
| ▸ | ABAT | P80404 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031911 | 0.83 | TYR (0.48) | TYRCYP2A6ALDH1A1ALDH1A3TSHR | |
| SCHEMBL9231758 | 0.83 | TYR (0.52) | TYRCYP2A6ALDH1A1ALDH1A3TSHR | |
| SCHEMBL16464746 | 0.80 | TYR (0.37) | TYRCYP2A6ALDH1A1ALDH1A3TSHR | |
| SCHEMBL3121559 | 0.80 | GPR55 (0.41) | TYRCYP2A6ALDH1A1ALDH1A3TSHR | |
| SCHEMBL29818670 | 0.79 | TYR (0.48) | TYRCYP2A6ALDH1A1ALDH1A3TSHR | |
| SCHEMBL6015149 | 0.78 | TYR (0.47) | TYRCYP2A6ALDH1A1ALDH1A3TSHR | |
| SCHEMBL29956336 | 0.78 | TYR (0.47) | TYRCYP2A6ALDH1A1ALDH1A3TSHR | |
| SCHEMBL3429786 | 0.78 | KDM4E (0.57) | TYRALDH1A1ALDH1A3TSHRKDM4E | |
| SCHEMBL6015150 | 0.78 | TYR (0.47) | TYRCYP2A6ALDH1A1ALDH1A3TSHR | |
| SCHEMBL18488343 | 0.78 | TYR (0.47) | TYRCYP2A6ALDH1A1ALDH1A3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| EP-0409729-B1 | Bi-aromatic thioesters, process for their preparation and their use in human or veterinary medicine and in cosmetics | CIRD GALDERMA (FR) | 1994-01-12 | — | — | EP | disclosed |
| EP-0409729-A1 | Bi-aromatic thioesters, process for their preparation and their use in human or veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1991-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | TYR 2328/4885CYP2A6 3547/4885ALDH1A1 4010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.