Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321403 | 0.98 | HRH3 (0.42) | FPR3FPR2SMN1; SMN2TP53CARM1 | |
| SCHEMBL9321377 | 0.98 | HRH3 (0.42) | FPR3FPR2SMN1; SMN2TP53CARM1 | |
| SCHEMBL9322327 | 0.98 | HRH3 (0.42) | FPR3FPR2SMN1; SMN2TP53CARM1 | |
| SCHEMBL9322157 | 0.93 | HRH3 (0.45) | FPR3FPR2SMN1; SMN2TP53CARM1 | |
| SCHEMBL9324718 | 0.93 | HRH3 (0.45) | FPR3FPR2SMN1; SMN2TP53CARM1 | |
| SCHEMBL9322427 | 0.92 | HRH3 (0.48) | FPR3FPR2SMN1; SMN2TP53CARM1 | |
| SCHEMBL9322361 | 0.92 | HRH3 (0.48) | FPR3FPR2SMN1; SMN2TP53CARM1 | |
| SCHEMBL9322390 | 0.92 | HRH3 (0.48) | FPR3FPR2SMN1; SMN2TP53CARM1 | |
| SCHEMBL9322203 | 0.92 | HRH3 (0.48) | FPR3FPR2SMN1; SMN2TP53CARM1 | |
| SCHEMBL9321347 | 0.92 | HRH3 (0.48) | FPR3FPR2SMN1; SMN2TP53CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235942-B1 | Alkylenediamine derivatives | NIPPON CHEMIPHAR CO (JP) | 1994-03-23 | — | — | EP | claimed |
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| EP-0235942-B1 | Alkylenediamine derivatives | NIPPON CHEMIPHAR CO (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |