Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | FPR3 | P25089 | 2/20 | 0.44 |
| ▸ | FPR2 | P25090 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322203 | 0.98 | HRH3 (0.48) | HRH3FPR3FPR2MAPTRAD52 | |
| SCHEMBL9322455 | 0.98 | HRH3 (0.48) | HRH3FPR3FPR2MAPTRAD52 | |
| SCHEMBL9322340 | 0.98 | HRH3 (0.48) | HRH3FPR3FPR2MAPTRAD52 | |
| SCHEMBL9322361 | 0.98 | HRH3 (0.48) | HRH3FPR3FPR2MAPTRAD52 | |
| SCHEMBL9322427 | 0.98 | HRH3 (0.48) | HRH3FPR3FPR2MAPTRAD52 | |
| SCHEMBL9321347 | 0.98 | HRH3 (0.48) | HRH3FPR3FPR2MAPTRAD52 | |
| SCHEMBL9322390 | 0.98 | HRH3 (0.48) | HRH3FPR3FPR2MAPTRAD52 | |
| SCHEMBL9322157 | 0.97 | HRH3 (0.45) | HRH3FPR3FPR2MAPTRAD52 | |
| SCHEMBL9322707 | 0.93 | FPR3 (0.40) | HRH3FPR3FPR2MAPTCARM1 | |
| SCHEMBL9321403 | 0.92 | HRH3 (0.42) | HRH3FPR3FPR2MAPTCARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |