Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213071 | 0.84 | MEN1 (0.40) | CYP2D6MEN1KMT2ACYP2C9ALOX15 | |
| SCHEMBL9321008 | 0.79 | MEN1 (0.38) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL9206117 | 0.79 | MEN1 (0.38) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL7864360 | 0.76 | MEN1 (0.38) | CYP2D6MEN1KMT2ACYP2C9ALOX15 | |
| SCHEMBL9213981 | 0.73 | KMT2A (0.39) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL7854234 | 0.73 | CYP2C9 (0.37) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL9205414 | 0.73 | MAPT (0.38) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL9210547 | 0.72 | MEN1 (0.36) | CYP2D6MEN1KMT2ACYP2C9ALOX15 | |
| SCHEMBL9203897 | 0.71 | KMT2A (0.37) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL5387737 | 0.70 | CYP2D6 (0.52) | CYP2D6MAPTGAAGRM5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356918-A | Oxazolidinone compounds and method of using the same as a vasodilator | SANKYO COMPANY, LTD. (JP) | 1994-10-18 | — | — | US | disclosed |
| US-5298516-A | Treatment of cardiovascular disorders, angina | SANKYO COMPANY, LIMITED (JP) | 1994-03-29 | — | — | US | disclosed |