Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 10/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213071 | 0.84 | MEN1 (0.40) | MEN1CYP2C9ALOX15CYP2C19KMT2A | |
| SCHEMBL7864448 | 0.81 | CACNA1G (0.37) | MEN1CYP2C9CYP2C19KMT2ACACNA1G | |
| SCHEMBL9210547 | 0.79 | MEN1 (0.36) | MEN1CYP2C9ALOX15CYP2C19KMT2A | |
| SCHEMBL9205054 | 0.79 | MEN1 (0.38) | MEN1CYP2C9ALOX15CYP2C19KMT2A | |
| SCHEMBL9322790 | 0.76 | CYP2D6 (0.42) | MEN1CYP2C9ALOX15CYP2C19KMT2A | |
| SCHEMBL9205414 | 0.76 | MAPT (0.38) | MEN1CYP2C9ALOX15CYP2C19KMT2A | |
| SCHEMBL7854234 | 0.76 | CYP2C9 (0.37) | MEN1CYP2C9ALOX15CYP2C19KMT2A | |
| SCHEMBL9203897 | 0.76 | KMT2A (0.37) | MEN1CYP2C9ALOX15CYP2C19KMT2A | |
| SCHEMBL9213981 | 0.72 | KMT2A (0.39) | MEN1CYP2C9ALOX15CYP2C19KMT2A | |
| SCHEMBL7854224 | 0.70 | PTGS2 (0.31) | CACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812835-B1 | OPTICALLY ACTIVE THIAZOLIDINONE DERIVATIVES | SANKYO CO (JP) | 2001-05-23 | — | — | EP | claimed |
| US-5891898-A | ANTIULCER AGENT | SANKYO COMPANY, LIMITED (JP) | 1999-04-06 | — | — | US | claimed |
| EP-0812835-A1 | OPTICALLY ACTIVE THIAZOLIDINONE DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1997-12-17 | — | — | EP | claimed |
| EP-0506434-B1 | Thiazolidinone and oxazolidinone derivatives, their preparation and their use as vasodilators | SANKYO CO (JP) | 1995-02-22 | — | — | EP | claimed |
| US-5356918-A | Oxazolidinone compounds and method of using the same as a vasodilator | SANKYO COMPANY, LTD. (JP) | 1994-10-18 | — | — | US | claimed |
| EP-0506434-A1 | Thiazolidinone and oxazolidinone derivatives, their preparation and their use as vasodilators | Sankyo Company Limited (JP) | 1992-09-30 | — | — | EP | claimed |
| EP-0812835-B1 | OPTICALLY ACTIVE THIAZOLIDINONE DERIVATIVES | SANKYO CO (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-5925658-A | PREVENTING OR TREATING ANGINA PECTORIS | SANKYO COMPANY, LIMITED (JP) | 1999-07-20 | — | — | US | disclosed |
| US-5891898-A | ANTIULCER AGENT | SANKYO COMPANY, LIMITED (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0812835-A1 | OPTICALLY ACTIVE THIAZOLIDINONE DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1997-12-17 | — | — | EP | disclosed |
| EP-0506434-B1 | Thiazolidinone and oxazolidinone derivatives, their preparation and their use as vasodilators | SANKYO CO (JP) | 1995-02-22 | — | — | EP | disclosed |
| US-5356918-A | Oxazolidinone compounds and method of using the same as a vasodilator | SANKYO COMPANY, LTD. (JP) | 1994-10-18 | — | — | US | disclosed |
| US-5298516-A | Treatment of cardiovascular disorders, angina | SANKYO COMPANY, LIMITED (JP) | 1994-03-29 | — | — | US | disclosed |
| EP-0506434-A1 | Thiazolidinone and oxazolidinone derivatives, their preparation and their use as vasodilators | Sankyo Company Limited (JP) | 1992-09-30 | — | — | EP | disclosed |