SCHEMBL9323219

SCHEMBL9323219

C=CCOC(=O)C(=O)OCC=C.C=CCON=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.38
MAPT P10636 3/20 0.36
TSHR P16473 2/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
KMT2A Q03164 4/20 0.33
ALDH1A1 P00352 3/20 0.33
MEN1 O00255 3/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SNCA P37840 1/20 0.33
MAPK1 P28482 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
PTP4A3 O75365 1/20 0.31
PTP4A1 Q93096 1/20 0.31
PKM P14618 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
APP P05067 1/20 0.30
KDM4E B2RXH2 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10497073 0.90 CYP3A4 (0.35) CYP3A4MAPTTSHRCACNA1BAPBA1
SCHEMBL177943 0.83 CYP3A4 (0.48) CYP3A4MAPTTSHRCACNA1BAPBA1
SCHEMBL27702 0.83
SCHEMBL27833417 0.83 KMT2A (0.45) KMT2AALDH1A1
Urea SCHEMBL11500350 0.82 MAPT (0.38) CYP3A4MAPTTSHRCACNA1BAPBA1
Ammonia Solution, Strong SCHEMBL15742962 0.81
SCHEMBL7512684 0.81 CYP3A4 (0.46) CYP3A4MAPTTSHRCACNA1BAPBA1
Allyl Alcohol SCHEMBL28109758 0.79 TSHR (0.45) TSHRKMT2AALDH1A1
Trimethylammonium SCHEMBL1905840 0.75 KMT2A (0.43) KMT2AALDH1A1MEN1
SCHEMBL10966895 0.74 CYP3A4 (0.45) CYP3A4MAPTTSHRCACNA1BAPBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0310191-B1 Process and reaction vessel for production of alkyl nitrite UNION CARBIDE CORP (US) 1994-02-16 EP disclosed
US-4908466-A Process and reaction vessel for production of alkyl nitrite UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) 1990-03-13 US disclosed
US-4879401-A Process for removal of impurities in alkyl nitrite formation UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) 1989-11-07 US disclosed
EP-0310191-A2 Process and reaction vessel for production of alkyl nitrite UNION CARBIDE CORPORATION (US) 1989-04-05 EP disclosed