Toluene

Toluene

SCHEMBL9323237

CC(C)c1ccccc1O.Cc1ccccc1

nearest known ligand 0.78

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.78
GABRB2 P47870 2/20 0.78
LMNA P02545 7/20 0.52
TSHR P16473 4/20 0.52
SLC6A2 P23975 2/20 0.52
HTR2B P41595 2/20 0.52
CHRM1 P11229 2/20 0.52
ADRA1A P35348 2/20 0.52
TRPA1 O75762 1/20 0.52
CYP1A2 P05177 3/20 0.48
CYP3A4 P08684 3/20 0.48
HIF1A Q16665 3/20 0.48
GABRB1 P18505 2/20 0.48
GABRG2 P18507 2/20 0.48
GABRB3 P28472 2/20 0.48
CA2 P00918 2/20 0.48
HPGD P15428 2/20 0.48
BLM P54132 2/20 0.48
PTGS1 P23219 2/20 0.48
FAAH O00519 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Peroxide SCHEMBL28937397 0.91 GABRA1 (0.95) GABRA1GABRB2LMNATSHRSLC6A2
Benzene SCHEMBL1841233 0.91 GABRA1 (0.95) GABRA1GABRB2LMNATSHRSLC6A2
SCHEMBL43297 0.89 GABRA1 (1.00) GABRA1GABRB2LMNATSHRSLC6A2
SCHEMBL15485453 0.89 GABRA1 (1.00) GABRA1GABRB2LMNATSHRSLC6A2
SCHEMBL29531559 0.89 GABRA1 (1.00) GABRA1GABRB2LMNATSHRSLC6A2
Ethane SCHEMBL5264203 0.86 GABRA1 (0.95) GABRA1GABRB2LMNATSHRSLC6A2
SCHEMBL28800546 0.86 GABRA1 (0.95) GABRA1GABRB2LMNATSHRSLC6A2
Phenol SCHEMBL5677167 0.84 GABRA1 (0.82) GABRA1GABRB2LMNATSHRSLC6A2
Hydrochloric Acid SCHEMBL6040027 0.84 GABRA1 (0.90) GABRA1GABRB2LMNATSHRSLC6A2
SCHEMBL29020580 0.82 GABRA1 (0.86) GABRA1GABRB2LMNATSHRSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0322247-B1 Decomposition of dihydroperoxide to resorcinol INDSPEC CHEMICAL CORP (US) 1994-02-16 EP disclosed
EP-0322246-B1 OXIDATION AND SUBSEQUENT DECOMPOSITION OF DIHYDROPEROXIDE INDSPEC CHEMICAL CORPORATION (a Delaware corporation) (US) 1992-03-04 EP disclosed
US-4847437-A Oxidation and subsequent decomposition of dihydroperoxide INDSPEC CHEMICAL CORPORATION (US) 1989-07-11 US disclosed
US-4847436-A LEWIS ACID CATALYSTS INDSPEC CHEMICAL CORPORATION (US) 1989-07-11 US disclosed
EP-0322246-A1 Oxidation and subsequent decomposition of dihydroperoxide INDSPEC CHEMICAL CORPORATION (a Delaware corporation) (US) 1989-06-28 EP disclosed
EP-0322247-A2 Decomposition of dihydroperoxide to resorcinol INDSPEC CHEMICAL CORPORATION (US) 1989-06-28 EP disclosed