Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.42 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321345 | 0.95 | SIGMAR1 (0.51) | SIGMAR1HRH3LTA4HSLC6A3CYP2D6 | |
| SCHEMBL9323771 | 0.94 | SIGMAR1 (0.58) | SIGMAR1HRH3LTA4HSLC6A3HRH1 | |
| SCHEMBL9323634 | 0.89 | SIGMAR1 (0.53) | SIGMAR1HRH3LTA4HSLC6A3CYP2D6 | |
| SCHEMBL9322390 | 0.85 | HRH3 (0.48) | SIGMAR1HRH3FPR3FPR2HRH1 | |
| SCHEMBL9321347 | 0.85 | HRH3 (0.48) | SIGMAR1HRH3FPR3FPR2HRH1 | |
| SCHEMBL9322361 | 0.85 | HRH3 (0.48) | SIGMAR1HRH3FPR3FPR2HRH1 | |
| SCHEMBL9322455 | 0.85 | HRH3 (0.48) | SIGMAR1HRH3FPR3FPR2HRH1 | |
| SCHEMBL9322203 | 0.85 | HRH3 (0.48) | SIGMAR1HRH3FPR3FPR2HRH1 | |
| SCHEMBL9322427 | 0.85 | HRH3 (0.48) | SIGMAR1HRH3FPR3FPR2HRH1 | |
| SCHEMBL9322340 | 0.85 | HRH3 (0.48) | SIGMAR1HRH3FPR3FPR2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |