Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 3/20 | 0.36 |
| ▸ | CES1 | P23141 | 3/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216180 | 1.00 | PAOX (0.56) | PAOXALDH1A1ACHEFAAHTSHR | |
| SCHEMBL5175809 | 1.00 | — | — | |
| SCHEMBL11662918 | 1.00 | PAOX (0.56) | PAOXALDH1A1ACHEFAAHTSHR | |
| SCHEMBL28789915 | 1.00 | PAOX (0.56) | PAOXALDH1A1ACHEFAAHTSHR | |
| SCHEMBL6527168 | 1.00 | PAOX (0.56) | PAOXALDH1A1ACHEFAAHTSHR | |
| SCHEMBL7831788 | 1.00 | PAOX (0.56) | PAOXALDH1A1ACHEFAAHTSHR | |
| SCHEMBL1115670 | 0.97 | — | — | |
| SCHEMBL724425 | 0.88 | — | — | |
| SCHEMBL7751445 | 0.87 | FAAH (0.52) | PAOXFAAHLMNAPPARGPPARD | |
| SCHEMBL16723870 | 0.85 | PAOX (0.72) | PAOXALDH1A1ACHETSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562253-B1 | MODIFIED CARBONYL REDUCTASE, GENE THEREOF, AND METHOD OF PRODUCING OPTICALLY ACTIVE ALCOHOLS USING THESE | KANEKA CORP (JP) | 2017-08-02 | — | — | EP | claimed |
| EP-1841745-B1 | PROCESS FOR THE MANUFACTURE OF A PRECURSOR OF VITAMIN B1 | DSM IP ASSETS BV (NL) | 2008-06-04 | — | — | EP | claimed |
| EP-0952143-B1 | Metal salt catalyzed process to oxazolines and subsequent formation of chloroketones | DOW AGROSCIENCES LLC (US) | 2003-01-22 | — | — | EP | claimed |
| EP-0872463-B1 | Chlorination of substituted alkenes using trichloroisocyanuric acid | DOW AGROSCIENCES LLC (US) | 2002-01-09 | — | — | EP | claimed |
| EP-0286969-B1 | PROCESS FOR PREPARING TRANS-2,2-DIMETHYL-3-(2,2-DICHLOROVINYL)-CYCLOPROPANE-CARBOXYLIC ACID | BAYER AG (DE) | 1992-06-03 | — | — | EP | claimed |
| EP-3769329-A2 | USE OF 1-CHLORO-2,3,3,3-TETRAFLUOROPROPENE FOR ISOLATING OR EXTINGUISHING ELECTRIC ARCS | ARKEMA FRANCE (FR) | 2021-01-27 | — | — | EP | disclosed |
| EP-3341951-A1 | USE OF HEXAFLUOROBUTENES FOR ISOLATING OR EXTINGUISHING ELECTRIC ARCS | Arkema France (FR) | 2018-07-04 | — | — | EP | disclosed |
| EP-3207554-A1 | ELECTRICAL INSULATION OR ELECTRIC ARC EXTINGUISHING GAS | Arkema France (FR) | 2017-08-23 | — | — | EP | disclosed |
| EP-2448939-B1 | 2,3-DIHYDRO-1H-IMIDAZO {1,2-A} PYRIMIDIN-5-ONE DERIVATIVES, THE PREPARATION AND PHARMACEUTICAL USE THEREOF | SANOFI SA (FR) | 2017-03-01 | — | — | EP | disclosed |
| EP-1589007-B1 | 5-membered heterocycle derivatives, production thereof and their use as medicaments | IPSEN PHARMA (FR) | 2015-06-03 | — | — | EP | disclosed |
| EP-2328883-B1 | METHOD FOR PREPARING NEBIVOLOL | ZACH SYSTEM (FR) | 2014-08-06 | — | — | EP | disclosed |
| EP-2448940-B1 | 6,7,8,9-tetrahydro-pyrimido{1,2-a} pyrimidin-4-one derivatives, their preparation and pharmaceutical use thereof | SANOFI SA (FR) | 2014-05-21 | — | — | EP | disclosed |
| WO-2001026656-A2 | 5-MEMBERED HETEROCYCLE DERIVATIVES AND USE THEREOF AS MONOAMINE OXIDASE INHIBITORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2001-04-19 | — | — | WO | disclosed |
| EP-0872474-A2 | Process for the preparation of chloroketones using oxazolines | ROHM AND HAAS COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| EP-0471609-B1 | Benzofuran Derivatives, Benzothiophenes, Indoles or Indolizines, Process for Production and Compositions containing them | SANOFI SA (FR) | 1996-11-27 | — | — | EP | disclosed |
| WO-1992021666-A1 | ANGIOTENSIN II RECEPTOR ANTAGONIST THIAZOLE DEVIVATIVES | LABORATOIRES UPSA (FR) | 1992-12-10 | — | — | WO | disclosed |
| EP-0486409-A1 | Method for protecting the products of multiplication of plants with the help of triazolyl/or imidazolyl-methyl allyl alcohols, and new compounds for this procedure | RHONE-POULENC AGROCHIMIE (FR) | 1992-05-20 | — | — | EP | disclosed |
| EP-0471609-A1 | Benzofuran Derivatives, Benzothiophenes, Indoles or Indolizines, Process for Production and Compositions containing them | SANOFI (FR) | 1992-02-19 | — | — | EP | disclosed |
| EP-0039646-A1 | 1,4-Benzodioxines, processes for their preparation and their use in therapy | RIOM LABORATOIRES- C.E.R.M. (Société Anonyme) (FR) | 1981-11-11 | — | — | EP | disclosed |
| US-4046752-A | Process for preparing an azo compound from a 2-aminothiazole diazo component | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-09-06 | — | — | US | disclosed |