SCHEMBL9323979

SCHEMBL9323979

CCNCCN(CC)CC(N)CN

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PLA2G1B P04054 1/20 0.36
PLA2G2A P14555 1/20 0.36
MEN1 O00255 1/20 0.30
GLA P06280 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylenediamine SCHEMBL28087230 0.85 CYP2C9 (0.31) PLA2G1BPLA2G2ACYP2C19
SCHEMBL6168746 0.79 PLA2G1B (0.52) PLA2G1BPLA2G2A
SCHEMBL17287875 0.78 CYP2C19 (0.33) PLA2G1BPLA2G2AMEN1GLACYP2C19
SCHEMBL134953 0.78 CYP2C19 (0.33) MEN1GLACYP2C19KMT2A
SCHEMBL250410 0.76 CYP2C19 (0.43) MEN1GLACYP2C19KMT2A
SCHEMBL3972281 0.76 CYP2C19 (0.43) MEN1GLACYP2C19KMT2A
SCHEMBL1543425 0.75 CYP2C19 (0.38) MEN1GLACYP2C19KMT2A
Hydrochloric Acid SCHEMBL29183274 0.74 CYP2C19 (0.41) MEN1GLACYP2C19KMT2A
SCHEMBL9079152 0.74 CYP2C19 (0.41) MEN1GLACYP2C19KMT2A
SCHEMBL8803099 0.74 CYP2C19 (0.41) MEN1GLACYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0303158-B1 Curable compounds, their preparation and use HOECHST AG (DE) 1994-06-15 EP disclosed
EP-0272665-B1 Aminourethanes, process for their preparation and their use HOECHST AG (DE) 1994-02-02 EP disclosed
EP-0303158-A2 Curable compounds, their preparation and use HOECHST AKTIENGESELLSCHAFT (DE) 1989-02-15 EP disclosed
EP-0272665-A2 Aminourethanes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1988-06-29 EP disclosed