SCHEMBL134953

SCHEMBL134953

CCNCCN(CC)CC(C)C

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
GLA P06280 1/20 0.33
CYP1A2 P05177 2/20 0.32
MAPK1 P28482 1/20 0.32
TSHR P16473 1/20 0.32
SLC22A1 O15245 1/20 0.31
LMNA P02545 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25472499 0.85 CYP1A2 (0.33) CYP2C19CYP1A2MAPK1SLC22A1
SCHEMBL3972281 0.81 CYP2C19 (0.43) CYP2C19MEN1KMT2AGLACYP1A2
SCHEMBL250410 0.81 CYP2C19 (0.43) CYP2C19MEN1KMT2AGLACYP1A2
SCHEMBL19501664 0.80 PRMT3 (0.44) CYP1A2MAPK1SLC22A1
SCHEMBL6141818 0.79 CYP2C9 (0.39) CYP2C19CYP1A2MAPK1
SCHEMBL9079152 0.79 CYP2C19 (0.41) CYP2C19MEN1KMT2AGLACYP1A2
Hydrochloric Acid SCHEMBL29183274 0.79 CYP2C19 (0.41) CYP2C19MEN1KMT2AGLACYP1A2
Ammonia Solution, Strong SCHEMBL11798888 0.79 CYP2C19 (0.41) CYP2C19MEN1KMT2AGLACYP1A2
SCHEMBL8803099 0.79 CYP2C19 (0.41) CYP2C19MEN1KMT2AGLACYP1A2
SCHEMBL9323979 0.78 PLA2G1B (0.36) CYP2C19MEN1KMT2AGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120058084-A1 Interferon Alpha Carrier Prodrugs ASCENDIS PHARMA AS (DK) 2012-03-08 US disclosed
EP-2403537-A1 INTERFERON ALPHA CARRIER PRODRUGS Ascendis Pharma A/S (DK) 2012-01-11 EP disclosed
WO-2010100220-A1 INTERFERON ALPHA CARRIER PRODRUGS ASCENDIS PHARMA AS (DK) 2010-09-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120058084-A1 Interferon Alpha Carrier Prodrugs IFNG, IFNAR1, IRF3 CYP2C19 98/4885MEN1 4083/4885KMT2A 4563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.