Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15874989 | 0.86 | MEN1 (0.52) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL23988090 | 0.83 | MEN1 (0.47) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL26195711 | 0.83 | MEN1 (0.49) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL25678057 | 0.82 | SMN1; SMN2 (0.63) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7110335 | 0.82 | MEN1 (0.48) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL23251929 | 0.81 | MEN1 (0.45) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL15435928 | 0.81 | MEN1 (0.51) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL23987984 | 0.81 | CXCR4 (0.52) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL7953543 | 0.81 | MEN1 (0.47) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL1494479 | 0.80 | SMN1; SMN2 (0.64) | KDM4EALDH1A1CYP1A2MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448929-A1 | NOVEL CONJUGATES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011001052-A1 | NOVEL CONJUGATES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2011-01-06 | — | — | WO | disclosed |