Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15435923 | 0.83 | NAMPT (0.43) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL16758742 | 0.81 | HSD11B1 (0.47) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL21855434 | 0.81 | SIGMAR1 (0.39) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL20745447 | 0.81 | HSD11B1 (0.47) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL15874989 | 0.81 | MEN1 (0.52) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL932436 | 0.81 | MEN1 (0.52) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL3553321 | 0.81 | NAMPT (0.44) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL30014967 | 0.80 | CACNA2D1 (0.39) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL23987984 | 0.80 | CXCR4 (0.52) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL15435916 | 0.79 | MEN1 (0.45) | MEN1KMT2AALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014016202-A1 | METHODS FOR CATALYTIC ALKYLATION OF NUCLEIC ACIDS | UNIVERSITÄT BASEL (CH) | 2014-01-30 | — | — | WO | disclosed |
| EP-2689847-A1 | Methods for catalytic alkylation of nucleic acids | Universität Basel (CH) | 2014-01-29 | — | — | EP | disclosed |