Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | FABP2 | P12104 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745850 | 0.84 | PPARA (0.61) | PPARACYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL255564 | 0.82 | CCR6 (0.50) | PPARACYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL8745843 | 0.80 | GRIN2B (0.43) | PPARACYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL28539048 | 0.80 | PPARA (0.45) | PPARACYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL7931525 | 0.78 | PPARA (0.44) | PPARACYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL5150961 | 0.78 | PPARA (0.40) | PPARACYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL10638540 | 0.76 | PPARA (0.42) | PPARACYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL10602615 | 0.76 | PPARA (0.42) | PPARACYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL10457158 | 0.76 | PPARA (0.47) | PPARACYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL8649157 | 0.76 | PPARA (0.42) | PPARACYP1A2CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393513-B1 | Preparation of a difluorohalomethoxybenzene | MITSUI TOATSU CHEMICALS (JP) | 1994-03-09 | — | — | EP | disclosed |
| US-5105021-A | Reacting metal phenolate with (di)bromo(chloro)difluoromethane in presence of promoter | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0393513-A1 | Preparation of a difluorohalomethoxybenzene | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-10-24 | — | — | EP | disclosed |