Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2096214 | 0.87 | CCR6 (0.43) | CCR6CHRNA7ALOX5MAPTMEN1 | |
| SCHEMBL2096216 | 0.87 | SLC6A4 (0.49) | CCR6CHRNA7ALOX5MGLLGRIN2B | |
| SCHEMBL254957 | 0.86 | MAPT (0.56) | MAPTMEN1CYP3A4KMT2AEPHX2 | |
| SCHEMBL10985063 | 0.84 | ALDH1A1 (0.59) | MEN1CYP3A4KMT2AALDH1A1 | |
| SCHEMBL3833768 | 0.84 | PPARA (0.63) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9324441 | 0.82 | PPARA (0.45) | CCR6CHRNA7ALOX5MAPTMEN1 | |
| SCHEMBL28539048 | 0.82 | PPARA (0.45) | CCR6CHRNA7ALOX5MAPTMEN1 | |
| SCHEMBL7931525 | 0.80 | PPARA (0.44) | CCR6CHRNA7ALOX5MAPTMEN1 | |
| SCHEMBL4923807 | 0.80 | EPHX2 (0.83) | MAPTMEN1KMT2AEPHX2ALDH1A1 | |
| SCHEMBL23484657 | 0.78 | GAA (0.46) | CHRNA7ALOX5PPARAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112159329-B | Co-production preparation method of o-amino trifluoromethoxybenzene and m-amino trifluoromethoxybenzene | 大连奇凯医药科技有限公司 | 2022-09-06 | — | — | CN | claimed |
| US-11279687-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. (US) | 2022-03-22 | — | — | US | claimed |
| CN-112159329-A | Co-production preparation method of o-amino trifluoromethoxybenzene and m-amino trifluoromethoxybenzene | 大连奇凯医药科技有限公司 | 2021-01-01 | — | — | CN | claimed |
| CN-111004095-A | Method for continuously/semi-continuously preparing trichloromethoxybenzene compounds | 大连奇凯医药科技有限公司 | 2020-04-14 | — | — | CN | claimed |
| CN-108059606-B | Method for preparing metaflumizone intermediate by using urea | 扬州工业职业技术学院 | 2020-03-27 | — | — | CN | claimed |
| CN-108129358-B | Clean and efficient metaflumizone synthesis process | 扬州工业职业技术学院 | 2020-03-24 | — | — | CN | claimed |
| CN-108129358-A | A kind of metaflumizone synthesis technology of clean and effective | 扬州工业职业技术学院 | 2018-06-08 | — | — | CN | claimed |
| CN-108059606-A | A kind of method that metaflumizone intermediate is prepared using urea | 扬州工业职业技术学院 | 2018-05-22 | — | — | CN | claimed |
| US-9169209-B2 | Compounds and compositions for the inhibition of NAMPT | FORMA TM, LLC (US) | 2015-10-27 | — | — | US | claimed |
| US-20140275057-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | Valo Health, LLC | 2014-09-18 | — | — | US | claimed |
| WO-2012150952-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | FORMA TM, LLC (US) | 2012-11-08 | — | — | WO | claimed |
| EP-0984920-B1 | NOVEL METHOD FOR PREPARING 2-TRIFLUORO-METHOXY-ANILINE | RHODIA CHIMIE SA (FR) | 2003-07-16 | — | — | EP | claimed |
| US-6121492-A | Method for preparing 2-trifluoro-methoxy-aniline | RHODIA CHIMIE (FR) | 2000-09-19 | — | — | US | claimed |
| EP-0984920-A1 | NOVEL METHOD FOR PREPARING 2-TRIFLUORO-METHOXY-ANILINE | RHODIA CHIMIE (FR) | 2000-03-15 | — | — | EP | claimed |
| WO-1998054121-A1 | NOVEL METHOD FOR PREPARING 2-TRIFLUORO-METHOXY-ANILINE | RHODIA-CHIMIE (FR) | 1998-12-03 | — | — | WO | claimed |
| EP-0064322-B1 | BENZENESULFONYL ISOCYANATES, ISOTHIOCYANATES, CHLORIDES, AND SULFONAMIDES HAVING A FLUORINATED SUBSTITUENT | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-05-22 | — | — | EP | claimed |
| US-4470930-A | Preparation of nuclear chlorinated aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-09-11 | — | — | US | claimed |
| CN-116730879-B | Method for selectively synthesizing 4-amino-N- (hetero) aryl sulfonamide compound | SHAANXI NORMAL UNIVERSITY (CN) | 2026-05-26 | — | — | CN | disclosed |
| EP-0023422-A2 | Herbicidal sulfonamides, preparation and use thereof, and compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-02-04 | — | — | EP | disclosed |
| US-4157344-A | REACTING PHENOLS WITH A PERHALOMETHANE AND HYDROGEN FLUORIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11279687-B2 | Compounds and compositions for the inhibition of NAMPT | NAMPT, NNT, NQO1 | CCR6 2462/4885CHRNA7 1805/4885ALOX5 1664/4885 |
| US-20140275057-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | NAMPT, NNMT, NAPRT | CCR6 3838/4885CHRNA7 2015/4885ALOX5 1271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.