Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 2/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9324275 | 0.77 | GRIA4 (0.35) | ALOX5CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL285337 | 0.74 | CCR1 (0.39) | ALOX5MAPTSMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL7508407 | 0.73 | — | — | |
| SCHEMBL20963155 | 0.68 | ALOX5 (0.36) | ALOX5MAPTSMN1; SMN2HIF1A | |
| SCHEMBL12462086 | 0.68 | ALOX5 (0.36) | ALOX5MAPTSMN1; SMN2HIF1A | |
| SCHEMBL6494251 | 0.67 | — | — | |
| SCHEMBL11198265 | 0.67 | TSHR (0.32) | — | |
| SCHEMBL18878202 | 0.67 | ALOX5 (0.38) | ALOX5MAPTSMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL12464829 | 0.67 | ALOX5 (0.39) | CXCR1CXCR2ALOX5CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL7744173 | 0.66 | IDO1 (0.42) | ALOX5MAPTSMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310941-A | Antiarrythmia agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1994-05-10 | — | — | US | disclosed |
| US-5208252-A | Antiarrhythmia | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-05-04 | — | — | US | disclosed |