Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP7 | P09237 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | FLT4 | P35916 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9324471 | 1.00 | PPARA (0.34) | PPARAENPP3ENPP1ALDH1A1MMP1 | |
| SCHEMBL8489165 | 0.85 | MEN1 (0.38) | ALDH1A1PPARG | |
| SCHEMBL8489163 | 0.85 | MEN1 (0.38) | ALDH1A1PPARG | |
| SCHEMBL8491832 | 0.83 | KMT2A (0.39) | ALDH1A1THRB | |
| SCHEMBL8491834 | 0.83 | KMT2A (0.39) | ALDH1A1THRB | |
| SCHEMBL7685397 | 0.82 | EPHX2 (0.40) | MMP2PPARG | |
| SCHEMBL7685401 | 0.82 | EPHX2 (0.40) | MMP2PPARG | |
| SCHEMBL8494935 | 0.79 | KMT2A (0.39) | GSTP1 | |
| SCHEMBL8492452 | 0.79 | HTT (0.37) | ALDH1A1 | |
| SCHEMBL8684077 | 0.79 | KMT2A (0.39) | GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371063-A | Herbicidal 4-benzoylisoxazoles | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1994-12-06 | — | — | US | disclosed |
| EP-0609797-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | disclosed |