Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.65 |
| ▸ | BID | P55957 | 3/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.54 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.54 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.54 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | EP300 | Q09472 | 1/20 | 0.54 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.54 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.54 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.54 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325227 | 1.00 | PLA2G2A (0.65) | PLA2G2ABIDMCL1BCL2L1BAK1 | |
| SCHEMBL9325294 | 1.00 | PLA2G2A (0.65) | PLA2G2ABIDMCL1BCL2L1BAK1 | |
| SCHEMBL9323942 | 1.00 | PLA2G2A (0.65) | PLA2G2ABIDMCL1BCL2L1BAK1 | |
| SCHEMBL9325513 | 1.00 | PLA2G2A (0.65) | PLA2G2ABIDMCL1BCL2L1BAK1 | |
| SCHEMBL9323696 | 1.00 | PLA2G2A (0.65) | PLA2G2ABIDMCL1BCL2L1BAK1 | |
| SCHEMBL9326084 | 1.00 | PLA2G2A (0.65) | PLA2G2ABIDMCL1BCL2L1BAK1 | |
| SCHEMBL9325773 | 1.00 | PLA2G2A (0.65) | PLA2G2ABIDMCL1BCL2L1BAK1 | |
| SCHEMBL9325746 | 0.98 | PLA2G2A (0.65) | PLA2G2ABIDMCL1BCL2L1BAK1 | |
| SCHEMBL9326059 | 0.89 | PLA2G2A (0.49) | PLA2G2ABIDMCL1BCL2L1BAK1 | |
| SCHEMBL9324833 | 0.89 | PLA2G2A (0.49) | PLA2G2ABIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374772-A | Skin disorders, antiinflammatory agents, cardiovascular disorders | HOFFMANN-LAROCHE INC. (US) | 1994-12-20 | — | — | US | claimed |
| EP-0601385-A1 | Disubstituted benzoic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-15 | — | — | EP | claimed |
| JP-6211743-A | — | — | None | — | — | JP | disclosed |
| US-5374772-A | Skin disorders, antiinflammatory agents, cardiovascular disorders | HOFFMANN-LAROCHE INC. (US) | 1994-12-20 | — | — | US | disclosed |
| JP-H06211743-A | SUBSTITUTED BENZOIC ACID | F HOFFMANN LA ROCHE AG | 1994-08-02 | — | — | JP | disclosed |
| EP-0601385-A1 | Disubstituted benzoic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-15 | — | — | EP | disclosed |