Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.38 |
| ▸ | AKT2 | P31751 | 3/20 | 0.38 |
| ▸ | AKT3 | Q9Y243 | 3/20 | 0.38 |
| ▸ | NAAA | Q02083 | 5/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335755 | 0.84 | CHRM2 (0.39) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL10589156 | 0.84 | CHRM2 (0.39) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9591880 | 0.79 | EPHX2 (0.39) | NAAAEPHX1TSHRGAAMAPK1 | |
| SCHEMBL9591882 | 0.79 | EPHX2 (0.39) | NAAAEPHX1TSHRGAAMAPK1 | |
| SCHEMBL9334436 | 0.76 | CHRM2 (0.41) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6448360 | 0.75 | NAAA (0.49) | AKT1AKT2AKT3NAAAEPHX1 | |
| SCHEMBL6442745 | 0.75 | NAAA (0.49) | AKT1AKT2AKT3NAAAEPHX1 | |
| SCHEMBL6448630 | 0.75 | NAAA (0.49) | AKT1AKT2AKT3NAAAEPHX1 | |
| SCHEMBL6445738 | 0.75 | NAAA (0.49) | AKT1AKT2AKT3NAAAEPHX1 | |
| SCHEMBL5549604 | 0.75 | EPHX2 (0.37) | NAAAEPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243645-B1 | Compounds having a nootropic activity, agents containing them and their use in the treatment and prophylaxis of cognitive malfunctions | HOECHST AG (DE) | 1994-03-16 | — | — | EP | disclosed |