Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325362 | 0.86 | BLM (0.37) | CYP3A4TSHR | |
| SCHEMBL9326168 | 0.84 | CYP3A4 (0.35) | CYP3A4TSHR | |
| SCHEMBL7293488 | 0.81 | CA2 (0.39) | CYP3A4TSHR | |
| SCHEMBL9326312 | 0.72 | — | — | |
| SCHEMBL9837929 | 0.71 | — | — | |
| SCHEMBL9482274 | 0.71 | — | — | |
| SCHEMBL8985035 | 0.71 | — | — | |
| SCHEMBL9484129 | 0.70 | — | — | |
| SCHEMBL9680134 | 0.69 | BLM (0.40) | CYP3A4TSHR | |
| SCHEMBL8985154 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171863-A | 2-trialkylsily-4-substituted furan derivatives | ALLERGAN, INC. (US) | 1992-12-15 | — | — | US | claimed |
| US-5322953-A | Antiinflammatory agents; intermediates for 2-furanone compounds | ALLERGAN, INC. (US) | 1994-06-21 | — | — | US | disclosed |
| US-5298633-A | Silane intermediates | ALLERGAN, INC. (US) | 1994-03-29 | — | — | US | disclosed |
| US-5171863-A | 2-trialkylsily-4-substituted furan derivatives | ALLERGAN, INC. (US) | 1992-12-15 | — | — | US | disclosed |
| US-5134128-A | Immunosuppressive and antiproliferative activity for psoriasis and calcium homeostasis | ALLERGAN, INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-5082954-A | Intermediates and processes for preparing 4-substituted 2-5(H)-furanones as anti-inflammatory agents | ALLERGAN, INC. (US) | 1992-01-21 | — | — | US | disclosed |
| EP-0372941-A2 | Anti-inflammatory 5-hydroxy-2-furanones | ALLERGAN, INC (US) | 1990-06-13 | — | — | EP | disclosed |