SCHEMBL932546

SCHEMBL932546

O=c1[nH]c(=O)c2nccnc2[nH]1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.46
ALDH1A1 P00352 4/20 0.46
BLM P54132 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
PMP22 Q01453 2/20 0.46
HSD17B10 Q99714 2/20 0.46
CYP1A2 P05177 1/20 0.46
PABPC1 P11940 1/20 0.46
ADORA2A P29274 1/20 0.46
ADORA2B P29275 1/20 0.46
CYP2C19 P33261 1/20 0.46
RAB9A P51151 1/20 0.46
CASP7 P55210 1/20 0.46
GDA Q9Y2T3 2/20 0.45
ACHE P22303 1/20 0.45
GAA P10253 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
RPS6KA3 P51812 2/20 0.44
RUNX1 Q01196 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29545868 1.00 KDM4E (0.46) KDM4EALDH1A1BLMTDP1PMP22
Water SCHEMBL6479622 0.98 KDM4E (0.44) KDM4EALDH1A1BLMTDP1PMP22
Hydrochloric Acid SCHEMBL28868510 0.98 KDM4E (0.44) KDM4EALDH1A1BLMTDP1PMP22
Hydrochloric Acid SCHEMBL30431695 0.98 KDM4E (0.44) KDM4EALDH1A1BLMTDP1PMP22
SCHEMBL9435433 0.89 RPS6KA3 (0.41) KDM4EALDH1A1BLMTDP1PMP22
Pterine SCHEMBL1512995 0.82 HSD17B10 (0.46) KDM4EALDH1A1PMP22HSD17B10MEN1
SCHEMBL30572345 0.80 GDA (0.44) KDM4EALDH1A1BLMTDP1PMP22
SCHEMBL340668 0.80 GDA (0.44) KDM4EALDH1A1BLMTDP1PMP22
SCHEMBL3961933 0.80 GDA (0.44) KDM4EALDH1A1BLMTDP1PMP22
SCHEMBL5441685 0.78 KDM4E (0.42) KDM4EALDH1A1BLMTDP1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1324 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4297723-B1 MICRONEEDLE COMPOSITIONS AND METHODS OF DELIVERY USING THE SAME BRIGHAM & WOMENS HOSPITAL INC (US) 2026-05-20 EP claimed
US-20250277175-A1 SINGLE-CHAMBER MICROBIAL ELECTROLYSIS CELL SYSTEM WITHOUT ION EXCHANGE MEMBRANE AND METHOD FOR PRODUCING CLEAN GAS SUCH AS HYDROGEN AND BIOGAS USING SAME PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) 2025-09-04 US claimed
WO-2025151713-A1 PROTEIN AND PEPTIDE VACCINES TARGETING METHANOGENS Arkea Bio Corp. (US) 2025-07-17 WO claimed
WO-2025151711-A1 NUCLEIC ACID VACCINES TARGETING METHANOGENS Arkea Bio Corp. (US) 2025-07-17 WO claimed
US-20250222082-A1 PROTEIN AND PEPTIDE VACCINES TARGETING METHANOGENS ARKEA BIO CORP (US) 2025-07-10 US claimed
WO-2025128700-A1 CELL-BASED VACCINES Arkea Bio Corp. (US) 2025-06-19 WO claimed
EP-4554616-A1 COMPOSITIONS AND METHODS FOR REDUCING METHANE EMISSIONS IN RUMINANT POPULATIONS Arkea Bio Corp. (US) 2025-05-21 EP claimed
US-20240424087-A1 MULTIEPITOPE SELF-ASSEMBLED NANOPARTICLE VACCINE PLATFORM (MSN-VACCINE PLATFORM) AND USES THERE OF TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) 2024-12-26 US claimed
US-20240392324-A1 Method for Microbiological Production of Hydrogen CEMVITA FACTORY INC (US) 2024-11-28 US claimed
WO-2024226815-A2 B-CELL EPITOPES OF TREPONEMA PALLIDUM ANTIGENS FOR USE IN A SYPHILIS VACCINE UNIVERSITY OF WASHINGTON (US) 2024-10-31 WO claimed
WO-1994022449-A1 THERAPEUTIC COMPOUNDS CELL THERAPEUTICS, INC. (US) 1994-10-13 WO claimed
WO-1994016704-A1 OXIME-SUBSTITUTED THERAPEUTIC COMPOUNDS CELL THERAPEUTICS, INC. (US) 1994-08-04 WO claimed
WO-1994015605-A1 ACETAL OR KETAL SUBSTITUTED THERAPEUTIC COMPOUNDS CELL THERAPEUTICS, INC. (US) 1994-07-21 WO claimed
WO-1994015606-A1 OLEFIN-SUBSTITUTED LONG CHAIN COMPOUNDS CELL THERAPEUTICS, INC. (US) 1994-07-21 WO claimed
WO-1994011370-A1 SUBSTITUTED AMINO ALKYL COMPOUNDS CELL THERAPEUTICS, INC. (US) 1994-05-26 WO claimed
WO-1994011001-A1 HYDROXYL-CONTAINING COMPOUNDS CELL THERAPEUTICS, INC. (US) 1994-05-26 WO claimed
US-5278043-A Chromophore compound HOFFMANN-LA ROCHE INC. (US) 1994-01-11 US claimed
EP-0566751-A1 DNA detection method F. HOFFMANN-LA ROCHE AG (CH) 1993-10-27 EP claimed
EP-0468187-A2 Cyclic amide derivatives Eisai Co., Ltd. (JP) 1992-01-29 EP claimed
US-4082911-A PROCESS FOR THE PREPARATION OF NUCLEOSIDES SCHERING AKTIENGESELLSCHAFT (DT) 1978-04-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250222082-A1 PROTEIN AND PEPTIDE VACCINES TARGETING METHANOGENS MCRS1, VIP, HM13 KDM4E 4403/4885ALDH1A1 4837/4885BLM 2678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.