SCHEMBL29545868

SCHEMBL29545868

O=c1[nH]c(=O)c2nccnc2[nH]1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 5/20 0.46
▸ ALDH1A1 P00352 4/20 0.46
▸ BLM P54132 2/20 0.46
▸ TDP1 Q9NUW8 2/20 0.46
▸ PMP22 Q01453 2/20 0.46
▸ HSD17B10 Q99714 2/20 0.46
▸ CYP1A2 P05177 1/20 0.46
▸ PABPC1 P11940 1/20 0.46
▸ ADORA2A P29274 1/20 0.46
▸ ADORA2B P29275 1/20 0.46
▸ CYP2C19 P33261 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ CASP7 P55210 1/20 0.46
▸ GDA Q9Y2T3 2/20 0.45
▸ ACHE P22303 1/20 0.45
▸ GAA P10253 2/20 0.44
▸ MEN1 O00255 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ RPS6KA3 P51812 2/20 0.44
▸ RUNX1 Q01196 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL932546 1.00 KDM4E (0.46) KDM4EALDH1A1BLMTDP1PMP22
Hydrochloric Acid SCHEMBL28868510 0.98 KDM4E (0.44) KDM4EALDH1A1BLMTDP1PMP22
Hydrochloric Acid SCHEMBL30431695 0.98 KDM4E (0.44) KDM4EALDH1A1BLMTDP1PMP22
Water SCHEMBL6479622 0.98 KDM4E (0.44) KDM4EALDH1A1BLMTDP1PMP22
SCHEMBL9435433 0.89 RPS6KA3 (0.41) KDM4EALDH1A1BLMTDP1PMP22
Pterine SCHEMBL1512995 0.82 HSD17B10 (0.46) KDM4EALDH1A1PMP22HSD17B10MEN1
SCHEMBL30572345 0.80 GDA (0.44) KDM4EALDH1A1BLMTDP1PMP22
SCHEMBL340668 0.80 GDA (0.44) KDM4EALDH1A1BLMTDP1PMP22
SCHEMBL3961933 0.80 GDA (0.44) KDM4EALDH1A1BLMTDP1PMP22
SCHEMBL5441685 0.78 KDM4E (0.42) KDM4EALDH1A1BLMTDP1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151713-A1 PROTEIN AND PEPTIDE VACCINES TARGETING METHANOGENS Arkea Bio Corp. (US) 2025-07-17 — — WO claimed
WO-2025151711-A1 NUCLEIC ACID VACCINES TARGETING METHANOGENS Arkea Bio Corp. (US) 2025-07-17 — — WO claimed
US-20250222082-A1 PROTEIN AND PEPTIDE VACCINES TARGETING METHANOGENS ARKEA BIO CORP (US) 2025-07-10 — — US claimed
WO-2025128700-A1 CELL-BASED VACCINES Arkea Bio Corp. (US) 2025-06-19 — — WO claimed
EP-4554616-A1 COMPOSITIONS AND METHODS FOR REDUCING METHANE EMISSIONS IN RUMINANT POPULATIONS Arkea Bio Corp. (US) 2025-05-21 — — EP claimed
WO-2024182781-A1 CORONAVIRUS COMPOSITIONS AND USES THEREOF Vir Biotechnology, Inc. (US) 2024-09-06 — — WO claimed
US-20240189408-A1 COMPOSITIONS AND METHODS FOR REDUCING METHANE EMISSIONS IN RUMINANT POPULATIONS Arkea Bio Corp. 2024-06-13 — — US claimed
WO-2024015366-A1 COMPOSITIONS AND METHODS FOR REDUCING METHANE EMISSIONS IN RUMINANT POPULATIONS Arkea Bio Corp. (US) 2024-01-18 — — WO claimed
CN-112979826-B Encephalitis B virus nanoparticle vaccine and preparation method and application thereof 华中农业大学 2022-04-08 — — CN claimed
EP-3674295-B1 HETEROCYCLIC COMPOUND, COMPOSITION INCLUDING HETEROCYCLIC COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2026-04-29 — — EP disclosed
US-12365782-B2 Compositions and methods for the degradation of waste polypropylene NOVOLOOP, INC. (US) 2025-07-22 — — US disclosed
WO-2025151713-A1 PROTEIN AND PEPTIDE VACCINES TARGETING METHANOGENS Arkea Bio Corp. (US) 2025-07-17 — — WO disclosed
WO-2025151711-A1 NUCLEIC ACID VACCINES TARGETING METHANOGENS Arkea Bio Corp. (US) 2025-07-17 — — WO disclosed
US-20250222082-A1 PROTEIN AND PEPTIDE VACCINES TARGETING METHANOGENS ARKEA BIO CORP (US) 2025-07-10 — — US disclosed
US-20220306829-A1 COMPOSITIONS AND METHODS FOR THE DEGRADATION OF WASTE POLYPROPYLENE NOVOLOOP INC (US) 2022-09-29 — — US disclosed
CN-113582873-B Method for preparing N-benzyl enamine by efficiently photo-catalytically oxidizing benzylamine 大连理工大学 2022-09-06 — — CN disclosed
WO-2022133259-A2 IMMUNOGENIC COMPOSITIONS THE SCRIPPS RESEARCH INSTITUTE (US) 2022-06-23 — — WO disclosed
WO-2022133255-A2 IMMUNOGENIC COMPOSITIONS THE SCRIPPS RESEARCH INSTITUTE (US) 2022-06-23 — — WO disclosed
CN-114630698-A Engineered HCV E2 immunogens and related vaccine compositions 斯克里普斯研究学院 2022-06-14 — — CN disclosed
CN-112979826-B Encephalitis B virus nanoparticle vaccine and preparation method and application thereof 华中农业大学 2022-04-08 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250222082-A1 PROTEIN AND PEPTIDE VACCINES TARGETING METHANOGENS MCRS1, VIP, HM13 KDM4E 4403/4885ALDH1A1 4837/4885BLM 2678/4885
US-20240189408-A1 COMPOSITIONS AND METHODS FOR REDUCING METHANE EMISSIONS IN RUMINANT POPULATIONS MT-CO2, CYB5R3, COX5A KDM4E 1943/4885ALDH1A1 1529/4885BLM 2636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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