Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | KDM1A | O60341 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325559 | 1.00 | GRIA1 (0.40) | GRIA1GRIA2GRIA3USP30ESR2 | |
| SCHEMBL9325765 | 0.96 | GRIA1 (0.41) | GRIA1GRIA2GRIA3USP30ESR2 | |
| SCHEMBL9325768 | 0.96 | GRIA1 (0.41) | GRIA1GRIA2GRIA3USP30ESR2 | |
| SCHEMBL9326560 | 0.90 | GRIA1 (0.42) | GRIA1GRIA2GRIA3USP30ESR2 | |
| SCHEMBL9326567 | 0.90 | GRIA1 (0.42) | GRIA1GRIA2GRIA3USP30ESR2 | |
| SCHEMBL25070381 | 0.86 | GRIA1 (0.45) | GRIA1GRIA2GRIA3USP30ESR2 | |
| SCHEMBL21649124 | 0.84 | SIGMAR1 (0.43) | GRIA1GRIA2GRIA3USP30ESR2 | |
| SCHEMBL9552824 | 0.83 | SIGMAR1 (0.42) | GRIA1GRIA2GRIA3USP30ESR2 | |
| SCHEMBL9552828 | 0.83 | SIGMAR1 (0.42) | GRIA1GRIA2GRIA3USP30ESR2 | |
| SCHEMBL2370340 | 0.81 | MEN1 (0.46) | GRIA1GRIA2GRIA3ESR2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392515-B1 | A difluoroalkylcyclohexyl-benzonitrile derivative | CHISSO CORP (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-5053162-A | Liquid crystals with low driving voltage | CHISSO CORPORATION (JP) | 1991-10-01 | — | — | US | disclosed |