Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF2R | P11717 | 7/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.37 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.37 |
| ▸ | LGALS4 | P56470 | 2/20 | 0.37 |
| ▸ | SELP | P16109 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2609681 | 0.88 | IGF2R (0.60) | IGF2RMAPK1LGALS8LGALS3LGALS4 | |
| SCHEMBL2609680 | 0.88 | IGF2R (0.69) | IGF2RMAPK1LGALS8LGALS3LGALS4 | |
| SCHEMBL2609678 | 0.87 | IGF2R (0.62) | IGF2RMAPK1LGALS8LGALS3LGALS4 | |
| SCHEMBL12944441 | 0.85 | IGF2R (0.62) | IGF2RMAPK1LGALS8LGALS3LGALS4 | |
| SCHEMBL16517931 | 0.85 | IGF2R (0.62) | IGF2RMAPK1LGALS8LGALS3LGALS4 | |
| SCHEMBL16492434 | 0.85 | IGF2R (0.62) | IGF2RMAPK1LGALS8LGALS3LGALS4 | |
| SCHEMBL932254 | 0.84 | IGF2R (0.61) | IGF2RMAPK1LGALS8LGALS3LGALS4 | |
| SCHEMBL2609671 | 0.84 | IGF2R (0.67) | IGF2RMAPK1LGALS8LGALS3LGALS4 | |
| SCHEMBL2609672 | 0.84 | IGF2R (0.67) | IGF2RMAPK1LGALS8LGALS3LGALS4 | |
| SCHEMBL12944442 | 0.84 | IGF2R (0.64) | IGF2RMAPK1LGALS8LGALS3LGALS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448600-B1 | COMPOUNDS TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR | INSERM INST NAT DE LA SANTÉ ET DE LA RECH MÉDICALE (FR) | 2016-03-30 | — | — | EP | disclosed |
| US-8962573-B2 | Compounds targeting the cation-independent mannose 6-phosphate receptor | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2015-02-24 | — | — | US | disclosed |
| EP-2448600-A1 | COMPOUNDS TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR | INSERM - Institut National de la Santé et de la Recherche Médicale (FR) | 2012-05-09 | — | — | EP | disclosed |
| US-20120093795-A1 | COMPOUNDS TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2012-04-19 | — | — | US | disclosed |
| WO-2011000958-A1 | COMPOUNDS TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2011-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120093795-A1 | COMPOUNDS TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR | M6PR, IGF2R, MPI | IGF2R 2/4885MAPK1 1862/4885LGALS8 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.