Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.75 |
| ▸ | HRH1 | P35367 | 1/20 | 0.75 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.75 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | FPR1 | P21462 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | RECQL | P46063 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | TEK | Q02763 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528755 | 1.00 | CYP2C19 (0.75) | CYP2C19HRH1SLC22A8POLBCYP3A4 | |
| SCHEMBL9580302 | 1.00 | CYP2C19 (0.75) | CYP2C19HRH1SLC22A8POLBCYP3A4 | |
| SCHEMBL4934732 | 1.00 | CYP2C19 (0.75) | CYP2C19HRH1SLC22A8POLBCYP3A4 | |
| Hydrochloric Acid SCHEMBL11802688 | 0.99 | CYP2C19 (0.74) | CYP2C19HRH1SLC22A8POLBCYP3A4 | |
| Water SCHEMBL10924164 | 0.99 | CYP2C19 (0.74) | CYP2C19HRH1SLC22A8POLBCYP3A4 | |
| SCHEMBL11546552 | 0.90 | CYP3A4 (0.71) | CYP2C19HRH1SLC22A8POLBCYP3A4 | |
| SCHEMBL11590266 | 0.90 | CYP2C19 (0.75) | CYP2C19HRH1SLC22A8POLBCYP3A4 | |
| SCHEMBL11590270 | 0.90 | CYP2C19 (0.75) | CYP2C19HRH1SLC22A8POLBCYP3A4 | |
| Hydrochloric Acid SCHEMBL11708138 | 0.89 | CYP2C19 (0.74) | CYP2C19HRH1SLC22A8POLBCYP3A4 | |
| SCHEMBL11707564 | 0.89 | CYP2C19 (0.74) | CYP2C19HRH1SLC22A8POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0294789-B1 | Process for preparing 6-/D(-)-Alpha-(4-ethyl-2,3-dioxo-1-piperazine-carboxamido)-phenylacetamido/pennicillanic acid | KRKA TOVARNA ZDRAVIL (YU) | 1994-10-12 | — | — | EP | claimed |
| EP-0317484-B1 | N,N'-carboxyl-bis-(4-ethyl-2,3-dioxo)-piperazine, process for the preparation thereof and use thereof | GEMA SA (ES) | 1994-03-16 | — | — | EP | claimed |
| US-5015736-A | Piperazine intermediates | GEMA, S.A. (ES) | 1991-05-14 | — | — | US | claimed |
| EP-0317484-A2 | N,N'-carboxyl-bis-(4-ethyl-2,3-dioxo)-piperazine, process for the preparation thereof and use thereof | GEMA S.A. (ES) | 1989-05-24 | — | — | EP | claimed |
| EP-0076066-B1 | PENICILLIN DERIVATIVES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-11-26 | — | — | EP | claimed |
| EP-0014651-B1 | TALAMPICILLIN 2-METHOXYPHENOXY ACETATE, PROCESS FOR ITS PREPARATION AND MEDICAMENTS CONTAINING IT | SANOFI S.A. (FR) | 1982-08-04 | — | — | EP | claimed |
| EP-0294789-B1 | Process for preparing 6-/D(-)-Alpha-(4-ethyl-2,3-dioxo-1-piperazine-carboxamido)-phenylacetamido/pennicillanic acid | KRKA TOVARNA ZDRAVIL (YU) | 1994-10-12 | — | — | EP | disclosed |
| EP-0317484-B1 | N,N'-carboxyl-bis-(4-ethyl-2,3-dioxo)-piperazine, process for the preparation thereof and use thereof | GEMA SA (ES) | 1994-03-16 | — | — | EP | disclosed |
| US-5229509-A | Process for the preparation of 3-chloro-cefem compounds | ANTIBIOTICOS, S.A. (ES) | 1993-07-20 | — | — | US | disclosed |
| US-5175348-A | Reacting acylal with hydrogen halide | SAUREFABRIK SCHWEIZERHALL (CH) | 1992-12-29 | — | — | US | disclosed |
| US-5171879-A | Reacting methylene dipivalate or derivatives with thionyl chloride; high purity | SAUREFABRIK SCHWEIZERHALL (CH) | 1992-12-15 | — | — | US | disclosed |
| EP-0473008-A2 | Improved process for preparing penicillins and cephalosporins | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1992-03-04 | — | — | EP | disclosed |
| US-5015736-A | Piperazine intermediates | GEMA, S.A. (ES) | 1991-05-14 | — | — | US | disclosed |
| US-3954733-A | ANTIBIOTIC | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-05-04 | — | — | US | disclosed |
| US-3951955-A | ANTIMICROBIAL | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-20 | — | — | US | disclosed |
| US-3951954-A | Novel oxofuryl ester derivatives of penicillin and cephalosporin | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1976-04-20 | — | — | US | disclosed |
| US-3951954-A | Novel oxofuryl ester derivatives of penicillin and cephalosporin | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1976-04-20 | — | — | US | disclosed |
| US-3941773-A | CRYSTALLINE | BRISTOL-MYERS COMPANY (US) | 1976-03-02 | — | — | US | disclosed |
| US-3939270-A | INFECTIOUS DISEASES | ASTRA LAKEMEDEL AKTIEBOLAG (SW) | 1976-02-17 | — | — | US | disclosed |
| US-3931153-A | BACTERICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-06 | — | — | US | disclosed |