Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.75 |
| ▸ | HRH1 | P35367 | 1/20 | 0.75 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.75 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | FPR1 | P21462 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | RECQL | P46063 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | TEK | Q02763 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9580302 | 1.00 | CYP2C19 (0.75) | CYP2C19HRH1SLC22A8POLBCYP3A4 | |
| SCHEMBL4934732 | 1.00 | CYP2C19 (0.75) | CYP2C19HRH1SLC22A8POLBCYP3A4 | |
| SCHEMBL9325621 | 1.00 | CYP2C19 (0.75) | CYP2C19HRH1SLC22A8POLBCYP3A4 | |
| Hydrochloric Acid SCHEMBL11802688 | 0.99 | CYP2C19 (0.74) | CYP2C19HRH1SLC22A8POLBCYP3A4 | |
| Water SCHEMBL10924164 | 0.99 | CYP2C19 (0.74) | CYP2C19HRH1SLC22A8POLBCYP3A4 | |
| SCHEMBL11546552 | 0.90 | CYP3A4 (0.71) | CYP2C19HRH1SLC22A8POLBCYP3A4 | |
| SCHEMBL11590266 | 0.90 | CYP2C19 (0.75) | CYP2C19HRH1SLC22A8POLBCYP3A4 | |
| SCHEMBL11590270 | 0.90 | CYP2C19 (0.75) | CYP2C19HRH1SLC22A8POLBCYP3A4 | |
| Hydrochloric Acid SCHEMBL11708138 | 0.89 | CYP2C19 (0.74) | CYP2C19HRH1SLC22A8POLBCYP3A4 | |
| SCHEMBL11707564 | 0.89 | CYP2C19 (0.74) | CYP2C19HRH1SLC22A8POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0169995-B1 | A HIGH YIELD PROCESS FOR PREPARING BETA-LACTAM ANTIBIOTICS HAVING A HIGH PURITY DEGREE | IBI- Istituto Biochimico Italiano Giovanni Lorenzini S.p.A. (IT) | 1993-04-14 | — | — | EP | disclosed |
| US-4625021-A | High yield process for preparing beta-lactam antibiotics having a high purity degree | ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI S.P.A. (IT) | 1986-11-25 | — | — | US | disclosed |
| EP-0169995-A2 | A high yield process for preparing beta-lactam antibiotics having a high purity degree | IBI- Istituto Biochimico Italiano Giovanni Lorenzini S.p.A. (IT) | 1986-02-05 | — | — | EP | disclosed |