⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23616491 | 0.86 | — | — | |
| SCHEMBL23452140 | 0.77 | LMNA (0.31) | — | |
| SCHEMBL8736339 | 0.77 | CYP3A4 (0.33) | — | |
| SCHEMBL4703252 | 0.74 | TSHR (0.32) | — | |
| SCHEMBL11949635 | 0.72 | GAA (0.31) | — | |
| SCHEMBL3697329 | 0.72 | CYP3A4 (0.41) | — | |
| SCHEMBL8906299 | 0.72 | CYP3A4 (0.37) | — | |
| SCHEMBL4254155 | 0.69 | — | — | |
| SCHEMBL7512269 | 0.69 | — | — | |
| SCHEMBL13567177 | 0.67 | SMN1; SMN2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001204-B | Process for preparing cis-2, 2,4, 4-tetramethylcyclobutane-1, 3-diol | 伊士曼化工公司 | 2020-11-20 | — | — | CN | claimed |
| EP-1913056-B1 | OPTICAL MEDIA COMPRISING POLYESTER COMPOSITIONS FORMED FROM 2,2,4,4,-TETRAMETHYL-1,3-CYCLOBUTANEDIOL AND 1,4,-CYCLOHEXANEDIMETHANOL | EASTMAN CHEM CO (US) | 2009-12-23 | — | — | EP | claimed |
| US-12577184-B2 | Production of 2,2,4,4-tetramethylcyclobutane-1,3-diol from isobutanol using a homogeneous catalyst | EASTMAN CHEMICAL COMPANY (US) | 2026-03-17 | — | — | US | disclosed |
| US-12390437-B2 | Itaconic acid derivatives and uses thereof intreating an inflammatory disease or a disease associated with an undesirable immune response | SITRYX THERAPEUTICS LIMITED (GB) | 2025-08-19 | — | — | US | disclosed |
| EP-3962602-B1 | ITACONIC ACID DERIVATIVES AND USES THEREOF IN TREATING AN INFLAMMATORY DISEASE OR A DISEASE ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE | SITRYX THERAPEUTICS LTD (GB) | 2025-06-25 | — | — | EP | disclosed |
| US-20230399278-A1 | PRODUCTION OF 2,2,4,4-TETRAMETHYLCYCLOBUTANE-1,3-DIOL FROM ISOBUTANOL USING A HOMOGENEOUS CATALYST | EASTMAN CHEMICAL COMPANY (US) | 2023-12-14 | — | — | US | disclosed |
| WO-2023193344-A1 | ALIPHATIC COPOLYCARBONATE AND PREPARATION METHOD THEREFOR | 中国科学院成都有机化学有限公司 | 2023-10-12 | — | — | WO | disclosed |
| CN-113166390-B | Thermoplastic resin for lens and lens comprising same | 帝人株式会社 | 2023-04-04 | — | — | CN | disclosed |
| US-20220265595-A1 | ITACONIC ACID DERIVATIVES AND USES THEREOF INTREATING AN INFLAMMATORY DISEASE OR A DISEASE ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE | SITRYX THERAPEUTICS LIMITED (GB) | 2022-08-25 | — | — | US | disclosed |
| CN-111684032-B | Interlayers comprising polyesteramide compositions | 首诺公司 | 2022-07-12 | — | — | CN | disclosed |
| WO-2022093681-A1 | RECYCLABLE POLYESTER POLYMERS FOR THERMOFORMED SHEETS AND MOLDED ARTICLES | AURIGA POLYMERS, INC. (US) | 2022-05-05 | — | — | WO | disclosed |
| WO-2002053643-A1 | POLYESTER COMPOSITIONS OF LOW RESIDUAL ALDEHYDE CONTENT | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-07-11 | — | — | WO | disclosed |
| WO-2001092379-A1 | THERMOPLASTIC MOLDING COMPOUNDS WITH IMPROVED SURFACE PROPERTIES AND IMPROVED STRUCTURAL HOMOGENEITY | BAYER AKTIENGESELLSCHAFT (DE) | 2001-12-06 | — | — | WO | disclosed |
| EP-1133529-A1 | THERMOPLASTIC RESINS WITH A LOW PROPORTION OF COARSE PARTICLES | Bayer Aktiengesellschaft (DE) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000027918-A1 | THERMOPLASTIC RESINS WITH A LOW PROPORTION OF COARSE PARTICLES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-05-18 | — | — | WO | disclosed |
| EP-0653462-A2 | Transparent polycarbonate PBT blends | Bayer Corporation (US) | 1995-05-17 | — | — | EP | disclosed |
| US-5401813-A | INCREASING THE TOTAL LIGHT TRANSMISSION OF A THERMOPLASTIC MOLDING MATERIAL BY BLENDING POLYBUTYLENE TEREPHTHALATE AND TWO AROMATIC POLYCARBONATES IN SPECIFIED AMOUNTS | MILES INC. (US) | 1995-03-28 | — | — | US | disclosed |
| US-5376736-A | Second polycarbonate contains cyclic bridging unit | MILES INC. (US) | 1994-12-27 | — | — | US | disclosed |
| US-5004569-A | Using phosphite containing oxetane groups as esterification catalyst | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-02 | — | — | US | disclosed |
| US-4225483-A | Boric acid esters and oxetanes for stabilizing phosphite-free polycarbonates | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-30 | — | — | US | disclosed |