Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | ABL1 | P00519 | 3/20 | 0.47 |
| ▸ | ABL2 | P42684 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046848 | 1.00 | POLB (0.58) | POLBAPEX1CTDSP1L3MBTL1MEN1 | |
| SCHEMBL11703812 | 0.88 | POLB (0.59) | POLBAPEX1CTDSP1L3MBTL1MEN1 | |
| SCHEMBL1636289 | 0.85 | POLB (0.55) | POLBAPEX1CTDSP1L3MBTL1MEN1 | |
| SCHEMBL30901879 | 0.85 | POLB (0.77) | POLBAPEX1CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL262215 | 0.85 | POLB (0.77) | POLBAPEX1CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL11777951 | 0.84 | TDP1 (0.53) | POLBAPEX1CTDSP1L3MBTL1MEN1 | |
| Water SCHEMBL6408071 | 0.84 | POLB (0.75) | POLBAPEX1CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL32680447 | 0.84 | POLB (0.61) | POLBAPEX1CTDSP1L3MBTL1MEN1 | |
| Water SCHEMBL7466907 | 0.84 | POLB (0.54) | POLBAPEX1CTDSP1L3MBTL1MEN1 | |
| SCHEMBL11775484 | 0.83 | SMN1; SMN2 (0.57) | POLBAPEX1CTDSP1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580797-A1 | BLENDS OF POLYPHENYLENE ETHER RESIN, A POLYETHERIMIDE SILOXANE COPOLYMER AND PENTAERYTHRITOL TETRABENZOATE | GENERAL ELECTRIC COMPANY (US) | 1994-02-02 | — | — | EP | disclosed |
| WO-1993016136-A1 | BLENDS OF POLYPHENYLENE ETHER RESIN, A POLYETHERIMIDE SILOXANE COPOLYMER AND PENTAERYTHRITOL TETRABENZOATE | GENERAL ELECTRIC COMPANY (US) | 1993-08-19 | — | — | WO | disclosed |