Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30081303 | 1.00 | ADH1B (0.34) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL5584080 | 0.86 | — | — | |
| SCHEMBL5584079 | 0.86 | — | — | |
| SCHEMBL20640999 | 0.86 | — | — | |
| SCHEMBL1587405 | 0.75 | CYP1A2 (0.39) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL6535865 | 0.75 | TSHR (0.47) | EPHX1 | |
| SCHEMBL548442 | 0.72 | — | — | |
| SCHEMBL3848698 | 0.71 | ADH1B (0.40) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL2021416 | 0.71 | ADH1B (0.40) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL6873949 | 0.71 | ADH1B (0.40) | ADH1BADH1CADH1AADH4ADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827638-B2 | Imidazopyrrolopyridine as inhibitors of the JAK family of kinases | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-28 | — | — | US | disclosed |
| EP-3555096-B1 | IMIDAZOPYRROLOPYRIDINE AS INHIBITORS OF THE JAK FAMILY OF KINASES | JANSSEN PHARMACEUTICA NV (BE) | 2022-11-23 | — | — | EP | disclosed |
| US-20210206768-A1 | IMIDAZOPYRROLOPYRIDINE AS INHIBITORS OF THE JAK FAMILY OF KINASES | JANSSEN PHARMACEUTICA NV (BE) | 2021-07-08 | — | — | US | disclosed |
| US-10981911-B2 | Imidazopyrrolopyridine as inhibitors of the JAK family of kinases | JANSSEN PHARMACEUTICA NV (BE) | 2021-04-20 | — | — | US | disclosed |
| US-20190322665-A1 | IMIDAZOPYRROLOPYRIDINE AS INHIBITORS OF THE JAK FAMILY OF KINASES | JANSSEN PHARMACEUTICA NV (BE) | 2019-10-24 | — | — | US | disclosed |
| EP-0334125-B1 | Low density silicone foam | GEN ELECTRIC (US) | 1994-06-08 | — | — | EP | disclosed |
| EP-0280499-B1 | Novel aminohydrocarbyl-substituted ketoximosilanes | DOW CORNING (US) | 1994-04-13 | — | — | EP | disclosed |
| EP-0281305-B1 | Method for preparing aminohydrocarbyl-substituted ketoximosilanes | DOW CORNING (US) | 1994-03-09 | — | — | EP | disclosed |
| EP-0417167-A1 | PROCESS FOR THE SYNTHESIS OF O-SUBSTITUTED OXIME COMPOUNDS | AlliedSignal Inc. (US) | 1991-03-20 | — | — | EP | disclosed |
| WO-1989011473-A1 | PROCESS FOR THE SYNTHESIS OF O-SUBSTITUTED OXIME COMPOUNDS | ALLIED-SIGNAL INC. (US) | 1989-11-30 | — | — | WO | disclosed |
| EP-0334125-A2 | Low density silicone foam | GENERAL ELECTRIC COMPANY (US) | 1989-09-27 | — | — | EP | disclosed |
| US-4808634-A | KETOXIME ADDITIVE TO REDUCE FOAM DENSITY | GENERAL ELECTRIC COMPANY (US) | 1989-02-28 | — | — | US | disclosed |
| EP-0158159-B1 | PROCESS FOR THE SYNTHESIS OF O-SUBSTITUTED OXIME COMPOUNDS AND THE CONVERSION THEREOF INTO THE CORRESPONDING HYDROXYLAMINE O-SUBSTITUTED | AlliedSignal Inc. (US) | 1988-10-05 | — | — | EP | disclosed |
| EP-0281305-A2 | Method for preparing aminohydrocarbyl-substituted ketoximosilanes | DOW CORNING CORPORATION (US) | 1988-09-07 | — | — | EP | disclosed |
| EP-0280499-A2 | Novel aminohydrocarbyl-substituted ketoximosilanes | DOW CORNING CORPORATION (US) | 1988-08-31 | — | — | EP | disclosed |
| US-4705878-A | Method for preparing aminohydrocarbyl-substituted ketoximosilanes | DOW CORNING CORPORATION (US) | 1987-11-10 | — | — | US | disclosed |
| US-4705877-A | Novel aminohydrocarbyl-substituted ketoximosilanes | DOW CORNING CORPORATION (US) | 1987-11-10 | — | — | US | disclosed |
| EP-0158159-A1 | Process for the synthesis of o-substituted oxime compounds and the conversion thereof into the corresponding hydroxylamine o-substituted | AlliedSignal Inc. (US) | 1985-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827638-B2 | Imidazopyrrolopyridine as inhibitors of the JAK family of kinases | JAK1, JAK2, JAK3 | ADH1B 4535/4885ADH1C 2290/4885ADH1A 2918/4885 |
| US-20210206768-A1 | IMIDAZOPYRROLOPYRIDINE AS INHIBITORS OF THE JAK FAMILY OF KINASES | JAK1, JAK2, JAK3 | ADH1B 4535/4885ADH1C 2290/4885ADH1A 2918/4885 |
| US-10981911-B2 | Imidazopyrrolopyridine as inhibitors of the JAK family of kinases | JAK1, JAK2, JAK3 | ADH1B 4535/4885ADH1C 2290/4885ADH1A 2918/4885 |
| US-20190322665-A1 | IMIDAZOPYRROLOPYRIDINE AS INHIBITORS OF THE JAK FAMILY OF KINASES | JAK1, JAK2, JAK3 | ADH1B 4535/4885ADH1C 2290/4885ADH1A 2918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.