Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326418 | 1.00 | ACHE (0.31) | ACHEMEN1KMT2ATDP1EPHX1 | |
| SCHEMBL9326428 | 1.00 | ACHE (0.31) | ACHEMEN1KMT2ATDP1EPHX1 | |
| SCHEMBL10772573 | 0.82 | CHRM5 (0.31) | — | |
| SCHEMBL10772568 | 0.82 | CHRM5 (0.31) | — | |
| SCHEMBL9402679 | 0.79 | — | — | |
| SCHEMBL9402672 | 0.79 | — | — | |
| SCHEMBL9327785 | 0.79 | — | — | |
| SCHEMBL9325462 | 0.76 | CYP1A2 (0.34) | — | |
| SCHEMBL9325449 | 0.76 | CYP1A2 (0.34) | — | |
| SCHEMBL9325457 | 0.76 | CYP1A2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361157-B1 | Phenyl pyridines | HOFFMANN LA ROCHE (CH) | 1994-03-02 | — | — | EP | disclosed |
| US-5284956-A | Liquid crystalline mixtures containing 2-(2-fluorophenyl) pyridines | HOFFMANN-LA ROCHE INC. (US) | 1994-02-08 | — | — | US | disclosed |
| EP-0361157-A1 | Phenyl pyridines | F. HOFFMANN-LA ROCHE AG (CH) | 1990-04-04 | — | — | EP | disclosed |