Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 5/20 | 0.47 |
| ▸ | HTR3A | P46098 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8218178 | 0.89 | HTR4 (0.45) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL8214403 | 0.88 | HTR4 (0.47) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL9090453 | 0.81 | HTR4 (0.61) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL9090458 | 0.81 | HTR4 (0.61) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL9090463 | 0.81 | HTR4 (0.61) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL30094418 | 0.81 | HTR4 (0.61) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL9092779 | 0.81 | HTR4 (0.51) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL9092771 | 0.81 | HTR4 (0.51) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL9092765 | 0.81 | HTR4 (0.51) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL9090158 | 0.78 | HTR4 (0.59) | HTR4HTR3AHTR1AADRA2CACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374637-A | Stimulate gastrointestinal motility | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-12-20 | — | — | US | claimed |