Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | RGS12 | O14924 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27919835 | 0.98 | KDM4E (0.47) | KDM4EMAPTHPGDHSD17B10ALDH1A1 | |
| SCHEMBL31478167 | 0.79 | AKR1B1 (0.58) | KDM4EMAPTHPGDHSD17B10ALDH1A1 | |
| SCHEMBL26133994 | 0.77 | ITGB3 (0.45) | KDM4EMAPTALDH1A1TSHRPOLB | |
| SCHEMBL3838996 | 0.77 | RXRB (0.62) | KDM4EMAPTHPGDHSD17B10ALDH1A1 | |
| SCHEMBL1206291 | 0.76 | HTR2A (0.40) | ITGB3ITGA2B | |
| SCHEMBL31514914 | 0.76 | HTR2A (0.40) | ITGB3ITGA2B | |
| SCHEMBL5527444 | 0.76 | RXRB (0.65) | KDM4EMAPTHPGDHSD17B10ALDH1A1 | |
| SCHEMBL19996854 | 0.76 | RXRB (0.60) | KDM4EMAPTHPGDHSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3710885 | 0.75 | HTR2A (0.39) | ITGB3ITGA2B | |
| SCHEMBL5173443 | 0.74 | GAA (0.48) | KDM4EMAPTHPGDHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166925-A1 | ISOINDOLINE DERIVATIVES FOR USE IN THE TREATMENT OF A VIRAL INFECTION | VIIV Healthcare UK Limited (GB) | 2017-05-17 | — | — | EP | disclosed |
| WO-2016005878-A1 | ISOINDOLINE DERIVATIVES FOR USE IN THE TREATMENT OF A VIRAL INFECTION | VIIV HEALTHCARE UK LIMITED (GB) | 2016-01-14 | — | — | WO | disclosed |
| CN-104045552-A | Medicinal compound as neuroprotective agent | SHANGHAI SIMCERE PHARMACEUTICAL RES CO LTD | 2014-09-17 | — | — | CN | disclosed |
| CN-103313968-A | Nampt and rock inhibitors | ABBVIE LAB | 2013-09-18 | — | — | CN | disclosed |
| US-5288749-A | Treating central nervous system or cardiovascular disorders | ABBOTT LABORATORIES (US) | 1994-02-22 | — | — | US | disclosed |