⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14150684 | 1.00 | — | — | |
| SCHEMBL933646 | 0.81 | — | — | |
| SCHEMBL933645 | 0.81 | — | — | |
| SCHEMBL10598207 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL26103757 | 0.79 | TDP1 (0.37) | — | |
| SCHEMBL10598214 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL19333596 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL17159774 | 0.78 | ALDH1A1 (0.39) | — | |
| SCHEMBL27281949 | 0.78 | MGAM (0.44) | — | |
| SCHEMBL28569353 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4584401-A | AMIDATION,ACYLATION,ALLYLATION AND OXIDATION OF BENZAMIDES TO FORMTRIS-GLYCOLS | BIOPHYSICA FOUNDATION (US) | 1986-04-22 | — | — | US | claimed |
| US-10307434-B2 | Nucleic acid prodrugs and methods of use thereof | WAVE LIFE SCIENCES LTD. (SG) | 2019-06-04 | — | — | US | disclosed |
| US-9744183-B2 | Nucleic acid prodrugs and methods of use thereof | WAVE LIFE SCIENCES LTD. (SG) | 2017-08-29 | — | — | US | disclosed |
| US-20160347784-A1 | NOVEL NUCLEIC ACID PRODRUGS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES PTE. LTD. (SG) | 2016-12-01 | — | — | US | disclosed |
| US-20120316224-A1 | NOVEL NUCLEIC ACID PRODRUGS AND METHODS OF USE THEREOF | ONTORII, INC (US) | 2012-12-13 | — | — | US | disclosed |
| EP-2451461-A1 | NOVEL NUCLEIC ACID PRODRUGS AND METHODS OF USE THEREOF | Ontorii, Inc (US) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011005761-A1 | NOVEL NUCLEIC ACID PRODRUGS AND METHODS USE THEREOF | ONTORII, INC (US) | 2011-01-13 | — | — | WO | disclosed |
| US-4835312-A | Production process of N-substituted amide compounds | MITSUI CHEMICALS, INCORPORATED (JP) | 1989-05-30 | — | — | US | disclosed |