Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807328 | 0.86 | SERPINE1 (0.48) | MAPTTDP1L3MBTL1PTGS2ALOX5 | |
| SCHEMBL29350333 | 0.86 | APEX1 (0.50) | APEX1MAPTTDP1L3MBTL1PTGS2 | |
| SCHEMBL76989 | 0.86 | APEX1 (0.50) | APEX1MAPTTDP1L3MBTL1PTGS2 | |
| SCHEMBL8844966 | 0.82 | TDP1 (0.60) | APEX1MAPTTDP1L3MBTL1PTGS2 | |
| SCHEMBL29084444 | 0.81 | HPGD (0.47) | APEX1MAPTTDP1L3MBTL1PTGS2 | |
| SCHEMBL11655989 | 0.81 | APEX1 (0.46) | APEX1MAPTTDP1L3MBTL1PTGS2 | |
| SCHEMBL27577575 | 0.79 | APEX1 (0.48) | APEX1MAPTTDP1L3MBTL1NPSR1 | |
| SCHEMBL9807325 | 0.78 | TNFRSF1A (0.49) | TDP1L3MBTL1PTGS2ALOX5TNFRSF1A | |
| SCHEMBL9635616 | 0.77 | APEX1 (0.45) | APEX1MAPTTDP1L3MBTL1PTGS2 | |
| Benzamide SCHEMBL21771957 | 0.77 | TDP1 (0.54) | APEX1MAPTTDP1L3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5359069-A | Non-migrating 1-hydrocarbyloxy hindered amine derivatives as polymer stabilizers | CIBA-GEIGY CORPORATION (US) | 1994-10-25 | — | — | US | disclosed |