Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326902 | 0.86 | APEX1 (0.45) | SERPINE1KMT2AMEN1ESR1ESR2 | |
| SCHEMBL78197 | 0.82 | ESR1 (0.66) | SERPINE1KMT2AMEN1ESR1ESR2 | |
| SCHEMBL9807325 | 0.81 | TNFRSF1A (0.49) | TNFRSF1APTGS2ALOX5PTGS1TDP1 | |
| SCHEMBL2374902 | 0.81 | SERPINE1 (0.54) | SERPINE1SMN1; SMN2GAANPSR1TNFRSF1A | |
| SCHEMBL11786628 | 0.78 | SELL (0.52) | SERPINE1KMT2AMEN1GAATNFRSF1A | |
| SCHEMBL9280957 | 0.78 | ALOX5 (0.55) | SERPINE1KMT2AMEN1ESR1ESR2 | |
| SCHEMBL77853 | 0.78 | NPSR1 (0.52) | KMT2AMEN1ESR1ESR2SMN1; SMN2 | |
| SCHEMBL8777982 | 0.78 | TSHR (0.58) | SERPINE1SMN1; SMN2GAANPSR1TNFRSF1A | |
| SCHEMBL29612711 | 0.78 | PTGS1 (0.48) | SERPINE1KMT2AMEN1ESR1ESR2 | |
| SCHEMBL1796301 | 0.78 | PTGS1 (0.48) | SERPINE1KMT2AMEN1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019613-A | Light stabilizers | CIBA-GEIGY CORPORATION (US) | 1991-05-28 | — | — | US | disclosed |
| US-4830770-A | EXTREME PRESSURE LUBRICANTS | CIBA-GEIGY CORPORATION (US) | 1989-05-16 | — | — | US | disclosed |