Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.51 |
| ▸ | HRH1 | P35367 | 4/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | KLF10 | Q13118 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006501 | 1.00 | HTR2A (0.51) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL6497248 | 0.85 | HTR2A (0.46) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL6497392 | 0.84 | HTR2A (0.45) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL9327063 | 0.81 | SLC6A4 (0.56) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL6497290 | 0.76 | NOS2 (0.54) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL13717320 | 0.74 | HTR2A (0.50) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL6498483 | 0.72 | SLC6A4 (0.54) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL6494143 | 0.71 | SLC6A4 (0.72) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL10439837 | 0.71 | SLC6A4 (0.56) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL6496956 | 0.70 | SLC6A4 (0.71) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0373836-B1 | Improvements in or relating to serotonin and norepinephrine uptake inhibitors | LILLY CO ELI (US) | 1994-03-16 | — | — | EP | claimed |
| JP-2218661-A | — | — | None | — | — | JP | disclosed |
| JP-H02218661-A | IMPROVED SEROTONIN AND NOREPINEPHIRINE TAKING-IN INHIBITOR | ELI LILLY & CO | 1990-08-31 | — | — | JP | disclosed |