SCHEMBL9327328

SCHEMBL9327328

S=P(Cl)(Sc1ccccc1)Sc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MGLL Q99685 1/20 0.41
HSD17B10 Q99714 1/20 0.41
KCNH2 Q12809 1/20 0.38
ALDH1A1 P00352 1/20 0.36
MAPK1 P28482 1/20 0.36
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
TSHR P16473 1/20 0.30
FFAR1 O14842 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333182 0.84 MAPT (0.41) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL1974102 0.78 MAPT (0.45) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL1975388 0.74 MAPT (0.41) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL1975625 0.74 MAPT (0.41) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL11124353 0.74 HPGD (0.41) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL2502560 0.74 KCNH2 (0.47) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL17788976 0.74 KCNH2 (0.42) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL9329799 0.74 MAPT (0.41) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL3732748 0.74 KCNH2 (0.47) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL10453256 0.74 KCNH2 (0.42) MAPTHPGDSMN1; SMN2MGLLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0358985-B1 Method of transhalogenating a halophosphorus compound with fluoride ETHYL CORP (US) 1994-03-16 EP disclosed
EP-0312790-B1 Process for transhalogenating a halophosphorus compound with fluoride ETHYL CORP (US) 1993-11-18 EP disclosed
US-5136075-A Process for transhalogenating a halophosphorus compound with fluoride ETHYL CORPORATION (US) 1992-08-04 US disclosed
US-5061818-A Fluorination with metal or ammonium fluoride in presence of pyridine halide salt ETHYL CORPORATION (US) 1991-10-29 US disclosed
US-5049691-A Process for transhalogenating a halophosphorous compound with anhydrous hydrogen fluoride ETHYL CORPORATION (US) 1991-09-17 US disclosed
US-4929745-A Transhalogenation of halophosphorus compounds EHTYL CORPORATION (US) 1990-05-29 US disclosed
EP-0358985-A1 Method of transhalogenating a halophosphorus compound with fluoride ETHYL CORPORATION (US) 1990-03-21 EP disclosed
US-4910324-A Using a metal or ammonium fluoride ETHYL CORPORATION (US) 1990-03-20 US disclosed
EP-0357048-A2 Process for transhalogenating a halophosphorus compound with hydrogen fluoride ALBEMARLE CORPORATION (US) 1990-03-07 EP disclosed
EP-0353598-A2 Transhalogenation of halophosphorus compounds ETHYL CORPORATION (US) 1990-02-07 EP disclosed