Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.56 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8792500 | 0.88 | CA2 (0.48) | CA2CA4CA1CA12CA3 | |
| SCHEMBL8792473 | 0.84 | CA2 (0.72) | CA2CA4CA1CA12CA3 | |
| Hydrochloric Acid SCHEMBL8793271 | 0.83 | CA2 (0.70) | CA2CA4CA1CA12CA3 | |
| SCHEMBL9327458 | 0.82 | CA2 (0.54) | CA2CA4CA1CA12CA3 | |
| SCHEMBL8791970 | 0.79 | CA2 (0.45) | CA2CA4CA1CA12CA3 | |
| SCHEMBL8791949 | 0.79 | CA2 (0.43) | CA2CA4CA1CA12CA3 | |
| SCHEMBL9329622 | 0.75 | CA2 (0.71) | CA2CA4CA1CA12CA3 | |
| SCHEMBL9328837 | 0.75 | CA2 (0.74) | CA2CA4CA1CA12CA3 | |
| Hydrochloric Acid SCHEMBL9327496 | 0.74 | CA2 (0.73) | CA2CA4CA1CA12CA3 | |
| SCHEMBL8792296 | 0.73 | CA2 (0.54) | CA2CA4CA1CA12CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308863-A | Carbonic anhydrase inhibitors | MERCK & CO., INC. (US) | 1994-05-03 | — | — | US | disclosed |