Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.47 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9332747 | 1.00 | EPHX2 (0.53) | EPHX2MEN1KMT2ACES2CES1 | |
| SCHEMBL9068432 | 0.93 | LTA4H (0.49) | EPHX2MEN1KMT2ACES2CES1 | |
| SCHEMBL8728626 | 0.93 | LTA4H (0.49) | EPHX2MEN1KMT2ACES2CES1 | |
| SCHEMBL8666117 | 0.85 | EPHX2 (0.54) | EPHX2MEN1KMT2ACES2CES1 | |
| SCHEMBL7104035 | 0.84 | EPHX2 (0.53) | EPHX2MEN1KMT2ACES2CES1 | |
| SCHEMBL27769116 | 0.83 | EPHX2 (0.51) | EPHX2MEN1KMT2ACES2CES1 | |
| SCHEMBL16657025 | 0.83 | LTA4H (0.69) | EPHX2MEN1KMT2ACES2CES1 | |
| SCHEMBL30008647 | 0.83 | LTA4H (0.69) | EPHX2MEN1KMT2ACES2CES1 | |
| SCHEMBL11870520 | 0.81 | MME (0.54) | EPHX2MEN1KMT2ACES2CES1 | |
| SCHEMBL18375940 | 0.80 | FAAH (0.54) | EPHX2MEN1KMT2AFAAHPSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011003455-A1 | METHOD FOR PRODUCING 4-(ALKYL)-1-(2-METHYL-3-(2,6-DIMETHYLMORPHOLINE)PROPYL) BENZOL COMPOUNDS | CILAG AG (CH) | 2011-01-13 | — | — | WO | disclosed |