Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23318194 | 0.81 | STAT3 (0.38) | CA12CA1CA2CA9CYP3A4 | |
| SCHEMBL11389659 | 0.81 | CA1 (0.50) | CA12CA1CA2CA9CYP3A4 | |
| SCHEMBL8331805 | 0.79 | GAA (0.51) | CA12CA1CA2CA9CYP3A4 | |
| SCHEMBL20577112 | 0.78 | CYP3A4 (0.43) | CYP3A4HSP90AA1HPGDTSHRHSD17B10 | |
| SCHEMBL11406014 | 0.78 | CYP3A4 (0.43) | CYP3A4HSP90AA1HPGDTSHRHSD17B10 | |
| SCHEMBL15920583 | 0.78 | TSHR (0.42) | CA12CA1CA2CA9HPGD | |
| SCHEMBL9327846 | 0.77 | CA12 (0.36) | CA12CA1CA2CA9STAT3 | |
| SCHEMBL9327906 | 0.77 | SERPINE1 (0.36) | CA12CA1CA2CA9CYP3A4 | |
| SCHEMBL9327839 | 0.77 | STAT3 (0.43) | CA12CA1CA2CA9CYP3A4 | |
| SCHEMBL28467235 | 0.77 | CA12 (0.40) | CA12CA1CA2CA9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296479-B1 | Fluorobenzoates and process for their production | IHARA CHEMICAL IND CO (JP) | 1994-03-30 | — | — | EP | disclosed |
| US-4916253-A | Fluorobenzoates and process for their production | IHARA CHEMICAL INDUSTRY COMPANY, LTD. (JP) | 1990-04-10 | — | — | US | disclosed |
| EP-0296479-A2 | Fluorobenzoates and process for their production | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 1988-12-28 | — | — | EP | disclosed |